Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10018
Official Symbol:BCL2L11
Other Aliases:BAM|BIM|BOD|BimEL|BimL
See related:HGNC:994|MIM:603827|HPRD:04828
Chromosome:2
Location:2q13
Gene Description:BCL2-like 11 (apoptosis facilitator)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0532
ORGANISM:human
Entrez Gene ID:10018
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:64547
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12125CBCerebellum8.324651956558239.6289975643158
12125CTXCerebral cortex10.60811662673957.51233816146851
12125HIPHippocampal region7.884657382965097.7916624546051
12125HPFHippocampal formation9.109627723693857.88689637184143
12125HYHypothalamus6.508716821670535.78481805324554
12125LSXLateral septal complex0.8164454549551010.860256642103195
12125MBMidbrain3.546251773834234.06897151470184
12125MYMedulla11.428511142730713.1957731246948
12125OLFOlfactory bulb18.472880363464413.9285907745361
12125PPons5.0338602066045.94723069667816
12125PALPallidum6.899790287017826.65632671117783
12125RHPRetrohippocampal region15.52009034156811.1598284244537
12125sAMYStriatum-like amygdalar nuclei6.255469322204594.38187539577484
12125STRStriatum7.044665098190315.25243377685547
12125STRdStriatum dorsal region6.133355379104614.33234935998917
12125STRvStriatum ventral region15.776144742965712.1092238426208
12125THThalamus5.156099319458014.58864545822144
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10018GO:0005515IPIFunctionprotein binding
10018GO:0005624TASComponentmembrane fraction
10018GO:0006915IEAProcessapoptosis
10018GO:0006917TASProcessinduction of apoptosis
10018GO:0016020IEAComponentmembrane
10018GO:0043065IEAProcesspositive regulation of apoptosis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_006529.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10018IPR009616Bim_NBim, N-terminal
10018BIM_HUMANO43521IPR009616Bim_NBim, N-terminal

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