Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10084
Official Symbol:PQBP1
Other Aliases:MRX55|MRXS3|MRXS8|NPW38|RENS1|SHS
See related:HGNC:9330|MIM:300463|HPRD:02354
Chromosome:X
Location:Xp11.23
Gene Description:polyglutamine binding protein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0138
ORGANISM:human
Entrez Gene ID:10084
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:54633
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
54633CBCerebellum14.316463917493818.0542231798172
54633CTXCerebral cortex39.011268392205232.3149985820055
54633HIPHippocampal region21.598918199539229.2972534298897
54633HPFHippocampal formation29.522101044654832.5959065258503
54633HYHypothalamus20.972125008702318.0083656311035
54633LSXLateral septal complex14.657701656222312.2833997681737
54633MBMidbrain21.316984742879919.408346503973
54633MYMedulla17.508860856294619.7879336178303
54633OLFOlfactory bulb26.707964062690724.3765822649002
54633PPons17.941295892000219.1540627479553
54633PALPallidum18.823237448930718.6655546426773
54633RHPRetrohippocampal region49.689258098602342.0837401747704
54633sAMYStriatum-like amygdalar nuclei36.366237893700630.2640269398689
54633STRStriatum19.223622217774415.3051135092974
54633STRdStriatum dorsal region15.243935056030811.8569428548217
54633STRvStriatum ventral region23.737289294600518.2517141848803
54633THThalamus23.49330189824121.927018225193
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10084GO:0003677TASFunctionDNA binding
10084GO:0003713TASFunctiontranscription coactivator activity
10084GO:0005634TASComponentnucleus
10084GO:0006350IEAProcesstranscription
10084GO:0006355TASProcessregulation of transcription, DNA-dependent
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_005701.1--NpwBPHPRD02354
NP_005701.1--Dim1HPRD02354
NP_005701.1--RNA polymeraseII, large subunitHPRD02354
NP_005701.151729-WW domain binding protein 11HPRD18293
NP_005701.110907NP_006692.1thioredoxin-like 4AHPRD18252
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10084PQBP1_HUMANO60828IPR001202WW_Rsp5_WWPWW/Rsp5/WWP

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.