Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10085
Official Symbol:EDIL3
Other Aliases:DEL1|MGC26287
See related:HGNC:3173|MIM:606018|HPRD:09350
Chromosome:5
Location:5q14
Gene Description:EGF-like repeats and discoidin I-like domains 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0902
ORGANISM:human
Entrez Gene ID:10085
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13612CBCerebellum3.704707622528083.29626321792603
13612CTXCerebral cortex1.397643208503721.08171617984772
13612HIPHippocampal region1.143789410591131.23756456375122
13612HPFHippocampal formation1.155345201492311.18277537822723
13612HYHypothalamus0.8312134742736820.284724533557892
13612LSXLateral septal complex0.5641035437583920.315112501382828
13612MBMidbrain2.775490522384642.0257465839386
13612MYMedulla6.295480728149415.04929971694946
13612OLFOlfactory bulb1.667273044586181.88703501224518
13612PPons3.176649093627933.13919878005981
13612PALPallidum2.0846414566041.56195759773254
13612RHPRetrohippocampal region0.9895586967468260.97116893529892
13612sAMYStriatum-like amygdalar nuclei0.519336163997650.312108516693115
13612STRStriatum0.7469423413276670.5030397772789
13612STRdStriatum dorsal region0.8411655426025390.58593738079071
13612STRvStriatum ventral region0.5681251883506770.433417588472366
13612THThalamus5.201598167419432.57089161872864
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10085GO:0005178TASFunctionintegrin binding
10085GO:0005509IEAFunctioncalcium ion binding
10085GO:0005515IEAFunctionprotein binding
10085GO:0007155IEAProcesscell adhesion
10085GO:0007275IEAProcessdevelopment
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_005702.3--Alphavbeta3 integrin receptorHPRD09350
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10085EDIL3_HUMANO43854IPR000152Asx_hydroxyl_SAspartic acid and asparagine hydroxylation site
10085EDIL3_HUMANO43854IPR001438EGF_2EGF-like, type 2
10085EDIL3_HUMANO43854IPR000742EGF_3EGF-like, type 3
10085EDIL3_HUMANO43854IPR001881EGF_Ca_bdEGF-like calcium-binding
10085EDIL3_HUMANO43854IPR006209EGF_likeEGF-like
10085EDIL3_HUMANO43854IPR013032EGF_like_regEGF-like region
10085EDIL3_HUMANO43854IPR000421FA58_CCoagulation factor 5/8 type, C-terminal

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