Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10130
Official Symbol:PDIA6
Other Aliases:ERP5|P5|TXNDC7
See related:HGNC:30168|HPRD:07504
Chromosome:2
Location:2p25.1
Gene Description:protein disulfide isomerase family A, member 6
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0075
ORGANISM:human
Entrez Gene ID:10130
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:71853
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
71853CBCerebellum45.4055023193359100.0
71853CTXCerebral cortex100.0100.0
71853HIPHippocampal region100.0100.0
71853HPFHippocampal formation100.0100.0
71853HYHypothalamus100.0100.0
71853LSXLateral septal complex100.0100.0
71853MBMidbrain100.0100.0
71853MYMedulla100.0100.0
71853OLFOlfactory bulb100.0100.0
71853PPons96.8598556518555100.0
71853PALPallidum100.0100.0
71853RHPRetrohippocampal region100.0100.0
71853sAMYStriatum-like amygdalar nuclei100.0100.0
71853STRStriatum100.0100.0
71853STRdStriatum dorsal region100.0100.0
71853STRvStriatum ventral region100.0100.0
71853THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10130GO:0003756TASFunctionprotein disulfide isomerase activity
10130GO:0005783TASComponentendoplasmic reticulum
10130GO:0005793IDAComponentER-Golgi intermediate compartment
10130GO:0006118IEAProcesselectron transport
10130GO:0006457TASProcessprotein folding
10130GO:0016853IEAFunctionisomerase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10130PDIA6_HUMANQ15084IPR000886ER_target_SEndoplasmic reticulum targeting sequence
10130PDIA6_HUMANQ15084IPR006662ThioredThioredoxin-related
10130PDIA6_HUMANQ15084IPR013766Thioredoxin_domThioredoxin domain
10130PDIA6_HUMANQ15084IPR006663Thioredox_dom2Thioredoxin domain 2

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