Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1015
Official Symbol:CDH17
Other Aliases:CDH16|FLJ26931|HPT-1|HPT1|MGC138218
See related:HGNC:1756|MIM:603017|HPRD:04312
Chromosome:8
Location:8q22.1
Gene Description:cadherin 17, LI cadherin (liver-intestine)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0114
ORGANISM:human
Entrez Gene ID:1015
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12629581
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Dorsolateral Prefrontal Cortex
Drug Effects:Upregulated/Downregulated
Fold Change:2.18 :: 2.54 :: 1.10 :: 0.51 :: -2.50 :: -2.48 :: -3.50
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12557CBCerebellum0.3000091910362240.600474178791046
12557CTXCerebral cortex0.3186914026737210.372660309076309
12557HIPHippocampal region0.1652444750070570.148660644888878
12557HPFHippocampal formation0.1364467144012450.17277891933918
12557HYHypothalamus0.09229190647602080.0836428701877594
12557LSXLateral septal complex0.7641755342483521.22685444355011
12557MBMidbrain0.07048746943473820.16954205930233
12557MYMedulla0.8360087871551510.959937334060669
12557OLFOlfactory bulb0.9489748477935791.89955246448517
12557PPons0.2088660299777980.407660156488419
12557PALPallidum0.1679469943046570.153414309024811
12557RHPRetrohippocampal region0.07952509820461270.19786524772644
12557sAMYStriatum-like amygdalar nuclei0.4168570339679720.360572785139084
12557STRStriatum0.2117739915847780.330955564975739
12557STRdStriatum dorsal region0.1734264492988590.208183154463768
12557STRvStriatum ventral region0.09628071635961530.559753358364105
12557THThalamus0.1448703557252880.166414007544518
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1015GO:0005215TASFunctiontransporter activity
1015GO:0005509IEAFunctioncalcium ion binding
1015GO:0005515IEAFunctionprotein binding
1015GO:0005624NRComponentmembrane fraction
1015GO:0005887NRComponentintegral to plasma membrane
1015GO:0006810NASProcesstransport
1015GO:0007155TASProcesscell adhesion
1015GO:0007156IEAProcesshomophilic cell adhesion
1015GO:0016020IEAComponentmembrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1015CAD17_HUMANQ12864IPR002126CadherinCadherin
1015CAD17_HUMANQ12864IPR013585ProtocadherinProtocadherin

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