Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1016
Official Symbol:CDH18
Other Aliases:CDH14|CDH14L|CDH24|EY-CADHERIN
See related:HGNC:1757|MIM:603019|HPRD:04314
Chromosome:5
Location:5p15.2-p15.1
Gene Description:cadherin 18, type 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0854
ORGANISM:human
Entrez Gene ID:1016
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.4 :: 1.7
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
320865CBCerebellum25.842386245727533.7193422317505
320865CTXCerebral cortex11.01049137115487.8795793056488
320865HIPHippocampal region1.283728063106541.4028097987175
320865HPFHippocampal formation6.995906352996836.9501576423645
320865HYHypothalamus7.199029922485355.494295835495
320865LSXLateral septal complex4.672573089599612.96270155906677
320865MBMidbrain5.953361272811894.84449172019958
320865MYMedulla9.198785543441778.8839738368988
320865OLFOlfactory bulb3.633540272712713.31333148479462
320865PPons6.07684838771825.58273279666901
320865PALPallidum4.192762494087223.54441583156586
320865RHPRetrohippocampal region13.896221637725812.3059229850769
320865sAMYStriatum-like amygdalar nuclei7.340166807174685.07814908027649
320865STRStriatum2.57009685039521.88319653272629
320865STRdStriatum dorsal region2.065075278282171.69629865884781
320865STRvStriatum ventral region1.288596630096440.859305500984192
320865THThalamus2.211570143699651.64803278446198
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1016GO:0005509IEAFunctioncalcium ion binding
1016GO:0005515IEAFunctionprotein binding
1016GO:0007155IEAProcesscell adhesion
1016GO:0007156IEAProcesshomophilic cell adhesion
1016GO:0016020IEAComponentmembrane
1016GO:0016021IEAComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004925.1--Cadherin 12HPRD04314
NP_004925.1--Cadherin 9HPRD04314
NP_004925.11016NP_004925.1cadherin 18, type 2 preproproteinHPRD04314
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1016CAD18_HUMANQ13634IPR002126CadherinCadherin
1016CAD18_HUMANQ13634IPR000233Cadherin_C_termCadherin cytoplasmic region
1016CAD18_HUMANQ13634IPR013585ProtocadherinProtocadherin

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