Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10280
Official Symbol:OPRS1
Other Aliases:FLJ25585|MGC3851|SIGMAR1|SR-BP1
See related:HGNC:8157|MIM:601978|HPRD:03580
Chromosome:9
Location:9p13.3
Gene Description:opioid receptor, sigma 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0062
ORGANISM:human
Entrez Gene ID:10280
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:18391
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18391CBCerebellum14.148896694183313.4396061897278
18391CTXCerebral cortex8.734149217605596.32537364959717
18391HIPHippocampal region5.720402956008912.81347131729126
18391HPFHippocampal formation7.88809347152715.73330950737
18391HYHypothalamus3.220580816268922.45199275016785
18391LSXLateral septal complex0.8368516042828560.886312048882246
18391MBMidbrain3.955352425575263.21251577138901
18391MYMedulla11.775927782058711.0196052789688
18391OLFOlfactory bulb19.184660911560113.2340898513794
18391PPons11.912622690200810.7306411266327
18391PALPallidum1.914641499519351.36373555660248
18391RHPRetrohippocampal region11.55914115905769.78273177146912
18391sAMYStriatum-like amygdalar nuclei4.508848667144783.31226313114166
18391STRStriatum1.563678801059721.09240788221359
18391STRdStriatum dorsal region0.7187765538692470.48794861137867
18391STRvStriatum ventral region3.23915225267411.77888351678848
18391THThalamus1.145917594432830.697987169027328
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10280GO:0000247IEAFunctionC-8 sterol isomerase activity
10280GO:0004872IEAFunctionreceptor activity
10280GO:0005783IEAComponentendoplasmic reticulum
10280GO:0006696IEAProcessergosterol biosynthesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10280IPR006716ERG2_S_rcpt_likeERG2 and sigma1 receptor-like protein

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