Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10399
Official Symbol:GNB2L1
Other Aliases:Gnb2-rs1|H12.3|HLC-7|PIG21|RACK1
See related:HGNC:4399|MIM:176981|HPRD:01503
Chromosome:5
Location:5q35.3
Gene Description:guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0518
ORGANISM:human
Entrez Gene ID:10399
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:83427
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14694CBCerebellum30.933605194091840.3733787536621
14694CTXCerebral cortex74.469505310058665.4183197021484
14694HIPHippocampal region69.343017578125100.0
14694HPFHippocampal formation61.180671691894582.1342849731445
14694HYHypothalamus38.072879791259836.4567718505859
14694LSXLateral septal complex45.322128295898443.7278289794922
14694MBMidbrain42.297962188720743.7470588684082
14694MYMedulla49.367832183837960.9159126281738
14694OLFOlfactory bulb64.655960083007862.146354675293
14694PPons40.534660339355548.4946022033691
14694PALPallidum33.096057891845735.3448867797852
14694RHPRetrohippocampal region48.667125701904347.4783058166504
14694sAMYStriatum-like amygdalar nuclei40.52448654174833.8733177185059
14694STRStriatum31.493942260742227.4071025848389
14694STRdStriatum dorsal region26.323038101196323.2962646484375
14694STRvStriatum ventral region39.578395843505930.8002605438232
14694THThalamus34.652523040771535.6165199279785
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10399GO:0005080ISSFunctionprotein kinase C binding
10399GO:0005102NASFunctionreceptor binding
10399GO:0007165ISSProcesssignal transduction
10399GO:0007205ISSProcessprotein kinase C activation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-26986NP_002559.1poly(A) binding protein, cytoplasmic 1HPRD05247
-22821NP_031394.1RAS p21 protein activator 3HPRD05537
-140890NP_631907.1splicing factor, arginine/serine-rich 12HPRD18043
NP_006089.1-CAB63939.1A73 proteinBIND169387
NP_006089.129967NP_038465.1suppression of tumorigenicityHPRD17447
NP_006089.122927NP_055097.1hyaluronan binding protein 4HPRD13628
NP_006089.122927NP_055097.1hyaluronan binding protein 4BIND258911
NP_006089.157085NP_065083.2angiotensin II receptor-associated proteinHPRD16379
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description

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