Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10501
Official Symbol:SEMA6B
Other Aliases:SEM-SEMA-Y|SEMA-VIB|SEMAN|Sema VIb|semaZ
See related:HGNC:10739|MIM:608873|HPRD:12322
Chromosome:19
Location:19p13.3
Gene Description:sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0011
ORGANISM:human
Entrez Gene ID:10501
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:20359
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
20359CBCerebellum27.066970825195334.3742561340332
20359CTXCerebral cortex73.986106872558660.2047500610352
20359HIPHippocampal region38.409393310546957.2295684814453
20359HPFHippocampal formation45.460254669189553.8663291931152
20359HYHypothalamus37.788536071777337.7184028625488
20359LSXLateral septal complex45.515003204345734.8974990844727
20359MBMidbrain21.836887359619120.4519996643066
20359MYMedulla40.851486206054747.0470237731934
20359OLFOlfactory bulb61.384647369384863.6544036865234
20359PPons25.568500518798828.1231365203857
20359PALPallidum25.811122894287125.9370155334473
20359RHPRetrohippocampal region58.558437347412151.1142692565918
20359sAMYStriatum-like amygdalar nuclei42.387687683105537.3472290039062
20359STRStriatum37.720054626464829.5024433135986
20359STRdStriatum dorsal region35.413608551025426.8240585327148
20359STRvStriatum ventral region42.304531097412133.808162689209
20359THThalamus48.672256469726645.941650390625
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10501GO:0004872IEAFunctionreceptor activity
10501GO:0007399IEAProcessnervous system development
10501GO:0016020IEAComponentmembrane
10501GO:0016021IEAComponentintegral to membrane
10501GO:0030154IEAProcesscell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10501IPR002165Plexin_repeatPlexin
10501IPR001627SemaSemaphorin/CD100 antigen
10501SEM6B_HUMANQ9H3T3IPR002165Plexin_repeatPlexin
10501SEM6B_HUMANQ9H3T3IPR000694PRO_richProline-rich region
10501SEM6B_HUMANQ9H3T3IPR001627SemaSemaphorin/CD100 antigen

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