Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1054
Official Symbol:CEBPG
Other Aliases:GPE1BP|IG/EBP-1
See related:HGNC:1837|MIM:138972|HPRD:00738
Chromosome:19
Location:19q13.11
Gene Description:CCAAT/enhancer binding protein (C/EBP), gamma
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0250
ORGANISM:human
Entrez Gene ID:1054
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.62
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12611CBCerebellum2.722468852996832.79046511650085
12611CTXCerebral cortex2.899873733520512.60437750816345
12611HIPHippocampal region3.510488748550423.3736424446106
12611HPFHippocampal formation2.239101409912112.00838947296143
12611HYHypothalamus1.547191381454471.11281418800354
12611LSXLateral septal complex1.808606147766111.23128056526184
12611MBMidbrain3.239944458007813.43521976470947
12611MYMedulla3.288782119750983.80303120613098
12611OLFOlfactory bulb2.950504541397092.84255743026733
12611PPons3.331520795822143.70381116867065
12611PALPallidum0.430442512035370.500883400440216
12611RHPRetrohippocampal region0.3020524680614470.282965362071991
12611sAMYStriatum-like amygdalar nuclei0.09292326122522350.132324859499931
12611STRStriatum0.3853104114532470.371931403875351
12611STRdStriatum dorsal region0.2654912173748020.355569779872894
12611STRvStriatum ventral region0.3505239486694340.200736373662949
12611THThalamus2.500464916229252.1358904838562
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1054GO:0001889ISSProcessliver development
1054GO:0005634ISSComponentnucleus
1054GO:0006337ISSProcessnucleosome disassembly
1054GO:0006338ISSProcesschromatin remodeling
1054GO:0006350IEAProcesstranscription
1054GO:0006355IEAProcessregulation of transcription, DNA-dependent
1054GO:0006955ISSProcessimmune response
1054GO:0008134IDAFunctiontranscription factor binding
1054GO:0030183ISSProcessB cell differentiation
1054GO:0042267ISSProcessnatural killer cell mediated cytotoxicity
1054GO:0043353ISSProcessenucleate erythrocyte differentiation
1054GO:0043388TASProcesspositive regulation of DNA binding
1054GO:0043433ISSProcessnegative regulation of transcription factor activity
1054GO:0043565IDAFunctionsequence-specific DNA binding
1054GO:0045078ISSProcesspositive regulation of interferon-gamma biosynthesis
1054GO:0045739IEPProcesspositive regulation of DNA repair
1054GO:0046982IDAFunctionprotein heterodimerization activity
1054GO:0051091TASProcesspositive regulation of transcription factor activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-22809NP_036200.2activating transcription factor 5HPRD05906
NP_001797.1--UbiquitinHPRD00738
NP_001797.122809-Activating transcription factor 5HPRD00738
NP_001797.11054NP_001797.1CCAAT/enhancer binding protein gammaHPRD00738
NP_001797.12353NP_005243.1v-fos FBJ murine osteosarcoma viral oncogene homologHPRD01275
NP_001797.12353NP_005243.1v-fos FBJ murine osteosarcoma viral oncogene homologHPRD00738
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1054CEBPG_HUMANP53567IPR011700bZIP_2Basic leucine zipper
1054CEBPG_HUMANP53567IPR004827TF_bZIPBasic-leucine zipper (bZIP) transcription factor

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