Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10591
Official Symbol:C6orf108
Other Aliases:RCL|RP3-330M21.3|dJ330M21.3
See related:HGNC:21218|HPRD:06707
Chromosome:6
Location:6p21.1
Gene Description:chromosome 6 open reading frame 108
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0089
ORGANISM:human
Entrez Gene ID:10591
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.49 :: -0.24 :: -0.15 :: -0.07 :: -0.36 :: 0.22 :: -0.40 :: -0.20 :: -0.31 :: -0.27
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
381101CBCerebellum5.195287227630626.43463754653931
381101CTXCerebral cortex9.945569992065437.1773829460144
381101HIPHippocampal region5.982976436614996.12520170211792
381101HPFHippocampal formation5.410486698150635.32269287109375
381101HYHypothalamus1.245907545089721.2194732427597
381101LSXLateral septal complex0.1829361766576770.0954944938421249
381101MBMidbrain0.9634841680526731.19403183460236
381101MYMedulla3.294732809066773.64090085029602
381101OLFOlfactory bulb9.076405525207527.2614049911499
381101PPons1.564344644546511.77944028377533
381101PALPallidum2.83137297630312.52389216423035
381101RHPRetrohippocampal region4.138229370117193.69371628761292
381101sAMYStriatum-like amygdalar nuclei1.692498207092291.40617060661316
381101STRStriatum3.674628257751462.81739854812622
381101STRdStriatum dorsal region3.737583398818973.0529248714447
381101STRvStriatum ventral region6.301930904388433.76919484138489
381101THThalamus1.637531280517581.57905697822571
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10591GO:0005634TASComponentnucleus
10591GO:0008283TASProcesscell proliferation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10591RCL_HUMANO43598IPR007710N_deoxyrib_transNucleoside 2-deoxyribosyltransferase

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