Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10628
Official Symbol:TXNIP
Other Aliases:EST01027|HHCPA78|THIF|VDUP1
See related:HGNC:16952|MIM:606599|HPRD:05964
Chromosome:1
Location:1q21.1
Gene Description:thioredoxin interacting protein
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0144
ORGANISM:human
Entrez Gene ID:10628
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:56338
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIM0904
ORGANISM:human
Entrez Gene ID:10628
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-1.4 :: -1.4 :: -2.3 :: -4.2
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
56338CBCerebellum1.734070340792342.87347300847371
56338CTXCerebral cortex1.28015549977621.50204334656398
56338HIPHippocampal region2.837324539820353.98882540067037
56338HPFHippocampal formation2.690374692281093.58503691355387
56338HYHypothalamus3.19282277425132.58470249176025
56338LSXLateral septal complex3.450476507345843.55870258808136
56338MBMidbrain1.713590383529662.53464818000793
56338MYMedulla2.721183617909754.49272147814433
56338OLFOlfactory bulb3.437312881151833.19292362531026
56338PPons3.962171077728276.27282351255417
56338PALPallidum1.488179524739581.72468070189158
56338RHPRetrohippocampal region2.235690315564472.5982019106547
56338sAMYStriatum-like amygdalar nuclei3.058733006318414.49530553817749
56338STRStriatum2.323083082834882.59642044703166
56338STRdStriatum dorsal region1.786440531412761.92787810166677
56338STRvStriatum ventral region1.963280280431111.81479169925054
56338THThalamus2.716227551301323.07496174176534
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10628GO:0000004NDProcessbiological process unknown
10628GO:0005554NDFunctionmolecular function unknown
10628GO:0008372NDComponentcellular component unknown
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_006463.2--FAZFHPRD05964
NP_006463.2--PLZFHPRD05964
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10628IPR011022Arrestin_CArrestin, C-terminal
10628IPR011021Arrestin_NArrestin, N-terminal

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