Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10745
Official Symbol:PHTF1
Other Aliases:PHTF
See related:HGNC:8939|MIM:604950|HPRD:09227
Chromosome:1
Location:1p13
Gene Description:putative homeodomain transcription factor 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0310
ORGANISM:human
Entrez Gene ID:10745
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.56
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
18685CBCerebellum2.801141262054443.27732539176941
18685CTXCerebral cortex4.782474994659423.49191069602966
18685HIPHippocampal region3.664697885513313.13814973831177
18685HPFHippocampal formation2.787124395370482.37223076820374
18685HYHypothalamus1.142275929450991.30085110664368
18685LSXLateral septal complex0.4907519817352290.551210761070251
18685MBMidbrain3.131080865859993.00450015068054
18685MYMedulla3.593447446823123.69862079620361
18685OLFOlfactory bulb6.39866685867314.25857830047607
18685PPons3.704898595809945.14090919494629
18685PALPallidum0.9768873453140260.801507711410522
18685RHPRetrohippocampal region1.43032860755921.31889367103577
18685sAMYStriatum-like amygdalar nuclei0.7789418697357180.661271214485168
18685STRStriatum1.808303475379941.4966117143631
18685STRdStriatum dorsal region2.028346776962281.82288420200348
18685STRvStriatum ventral region2.027503967285161.23358023166656
18685THThalamus3.044990062713622.21520447731018
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10745GO:0003700TASFunctiontranscription factor activity
10745GO:0005634IEAComponentnucleus
10745GO:0006350IEAProcesstranscription
10745GO:0006355IEAProcessregulation of transcription, DNA-dependent
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10745PHTF1_HUMANQ9UMS5

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