Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10772
Official Symbol:FUSIP1
Other Aliases:FUSIP2|NSSR|SRp38|SRrp40|TASR|TASR1|TASR2
See related:HGNC:16713|MIM:605221|HPRD:05562
Chromosome:1
Location:1p36.11
Gene Description:FUS interacting protein (serine/arginine-rich) 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0255
ORGANISM:human
Entrez Gene ID:10772
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.54
KARG Evidence 2
KARG ID:HOT0164
ORGANISM:human
Entrez Gene ID:10772
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:HOT0081
ORGANISM:human
Entrez Gene ID:10772
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 4
KARG ID:HOT0080
ORGANISM:human
Entrez Gene ID:10772
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
14105CBCerebellum28.09670066833531.4351749420166
14105CTXCerebral cortex61.930767059326242.5381507873535
14105HIPHippocampal region53.984214782714878.2970123291016
14105HPFHippocampal formation50.912807464599659.8474617004395
14105HYHypothalamus31.515787124633822.4044227600098
14105LSXLateral septal complex29.587554931640620.0152835845947
14105MBMidbrain29.636293411254923.9109764099121
14105MYMedulla27.932987213134827.4039783477783
14105OLFOlfactory bulb55.758052825927744.6045684814453
14105PPons24.336439132690423.2052593231201
14105PALPallidum24.710311889648419.0176200866699
14105RHPRetrohippocampal region45.95825195312535.7227783203125
14105sAMYStriatum-like amygdalar nuclei49.009227752685532.4706687927246
14105STRStriatum42.321426391601628.4001884460449
14105STRdStriatum dorsal region46.649311065673832.0261573791504
14105STRvStriatum ventral region31.383855819702119.6169338226318
14105THThalamus29.52405548095724.3998394012451
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10772GO:0000166IEAFunctionnucleotide binding
10772GO:0000244NASProcessassembly of spliceosomal tri-snRNP
10772GO:0000398IDAProcessnuclear mRNA splicing, via spliceosome
10772GO:0003676IEAFunctionnucleic acid binding
10772GO:0005634ICComponentnucleus
10772GO:0005634ISSComponentnucleus
10772GO:0005654IDAComponentnucleoplasm
10772GO:0005737ICComponentcytoplasm
10772GO:0005737ISSComponentcytoplasm
10772GO:0005737NASComponentcytoplasm
10772GO:0006376IDAProcessmRNA splice site selection
10772GO:0006376ISSProcessmRNA splice site selection
10772GO:0006406NASProcessmRNA export from nucleus
10772GO:0016482IDAProcesscytoplasmic transport
10772GO:0031202IDAFunctionRNA splicing factor activity, transesterification mechanism
10772GO:0045449ISSProcessregulation of transcription
10772GO:0045449NASProcessregulation of transcription
10772GO:0048025IDAProcessnegative regulation of nuclear mRNA splicing, via spliceosome
10772GO:0050733NASFunctionRS domain binding
10772GO:0051082NASFunctionunfolded protein binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-140890NP_631907.1splicing factor, arginine/serine-rich 12HPRD18043
NP_473357.129896NP_037425.1transformer-2 alphaBIND57825
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10772IPR000504RNP1_RNA_bdRNA-binding region RNP-1 (RNA recognition motif)
10772FUSIP_HUMANO75494IPR000504RNP1_RNA_bdRNA-binding region RNP-1 (RNA recognition motif)

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