Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:108
Official Symbol:ADCY2
Other Aliases:FLJ16822|FLJ45092|HBAC2|KIAA1060|MGC133314
See related:HGNC:233|MIM:103071|HPRD:00052
Chromosome:5
Location:5p15.3
Gene Description:adenylate cyclase 2 (brain)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0576
ORGANISM:human
Entrez Gene ID:108
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:81636
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
210044CBCerebellum9.2363313436508212.2915733456612
210044CTXCerebral cortex69.640981674194364.4630832672119
210044HIPHippocampal region71.042057037353567.8589859008789
210044HPFHippocampal formation69.769538879394566.4339962005615
210044HYHypothalamus37.156465530395537.7010440826416
210044LSXLateral septal complex42.907340049743749.9816906452179
210044MBMidbrain37.547114849090644.376612663269
210044MYMedulla24.585366725921632.0390100479126
210044OLFOlfactory bulb74.885877609252964.3338804244995
210044PPons24.109080791473430.7173175811768
210044PALPallidum41.648884773254454.9654979705811
210044RHPRetrohippocampal region68.327028274536164.4323921203613
210044sAMYStriatum-like amygdalar nuclei44.600260257720947.4233632087708
210044STRStriatum19.763130187988325.2226686477661
210044STRdStriatum dorsal region13.419378995895419.0743691921234
210044STRvStriatum ventral region22.15288639068627.4735941886902
210044THThalamus17.372480154037522.8583209514618
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
108GO:0000287IEAFunctionmagnesium ion binding
108GO:0004016NASFunctionadenylate cyclase activity
108GO:0006171NASProcesscAMP biosynthesis
108GO:0007242IEAProcessintracellular signaling cascade
108GO:0009190IEAProcesscyclic nucleotide biosynthesis
108GO:0016020IEAComponentmembrane
108GO:0016021NASComponentintegral to membrane
108GO:0016849IEAFunctionphosphorus-oxygen lyase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-2778NP_536350.1guanine nucleotide binding protein, alpha stimulating activity polypeptide 1 isoform cHPRD00761
-111NP_899200.1adenylate cyclase 5HPRD08973
AAP97285.1--GsalphaHPRD00052
AAP97285.1111-Adenylate cyclase 5HPRD00052
AAP97285.12778-Guanine nucleotide binding protein G(S), alpha subunitHPRD00052
NP_065433.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
108IPR001054A/G_cyclaseAdenylyl cyclase class-3/4/guanylyl cyclase
108IPR009398Aden_cycl_likeAdenylate cyclase-like

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.