Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10891
Official Symbol:PPARGC1A
Other Aliases:LEM6|PGC-1(alpha)|PGC-1v|PGC1|PGC1A|PPARGC1
See related:HGNC:9237|MIM:604517|HPRD:05155
Chromosome:4
Location:4p15.1
Gene Description:peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0151
ORGANISM:human
Entrez Gene ID:10891
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:19017
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10891GO:0000166IEAFunctionnucleotide binding
10891GO:0001659TASProcessthermoregulation
10891GO:0001678NASProcesscell glucose homeostasis
10891GO:0003677TASFunctionDNA binding
10891GO:0003723TASFunctionRNA binding
10891GO:0005634TASComponentnucleus
10891GO:0005665TASComponentDNA-directed RNA polymerase II, core complex
10891GO:0006094NASProcessgluconeogenesis
10891GO:0006350IEAProcesstranscription
10891GO:0006367TASProcesstranscription initiation from RNA polymerase II promoter
10891GO:0006397TASProcessmRNA processing
10891GO:0006461TASProcessprotein complex assembly
10891GO:0007005NASProcessmitochondrion organization and biogenesis
10891GO:0007586TASProcessdigestion
10891GO:0008134TASFunctiontranscription factor binding
10891GO:0008380TASProcessRNA splicing
10891GO:0016455TASFunctionRNA polymerase II transcription mediator activity
10891GO:0019395NASProcessfatty acid oxidation
10891GO:0030374TASFunctionligand-dependent nuclear receptor transcription coactivator activity
10891GO:0030521NASProcessandrogen receptor signaling pathway
10891GO:0035066TASProcesspositive regulation of histone acetylation
10891GO:0042594NASProcessresponse to starvation
10891GO:0045333TASProcesscellular respiration
10891GO:0045722TASProcesspositive regulation of gluconeogenesis
10891GO:0045893NASProcesspositive regulation of transcription, DNA-dependent
10891GO:0046321TASProcesspositive regulation of fatty acid oxidation
10891GO:0050681NASFunctionandrogen receptor binding
10891GO:0050821TASProcessprotein stabilization
10891GO:0050873TASProcessbrown fat cell differentiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10891PRGC1_HUMANQ9UBK2IPR000504RNP1_RNA_bdRNA-binding region RNP-1 (RNA recognition motif)

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