Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10965
Official Symbol:ACOT2
Other Aliases:Mte1|PTE2|ZAP128
See related:HGNC:18431|MIM:609972|HPRD:10173
Chromosome:14
Location:14q24.3
Gene Description:acyl-CoA thioesterase 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0233
ORGANISM:human
Entrez Gene ID:10965
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:171210
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
171281CBCerebellum0.00.0
171210CBCerebellum100.0100.0
171281CTXCerebral cortex0.00.0
171210CTXCerebral cortex100.0100.0
171281HIPHippocampal region0.00.0
171210HIPHippocampal region100.0100.0
171281HPFHippocampal formation0.00.0
171210HPFHippocampal formation100.0100.0
171281HYHypothalamus0.00.0
171210HYHypothalamus98.696182250976688.0733108520508
171281LSXLateral septal complex0.00.0
171210LSXLateral septal complex100.0100.0
171281MBMidbrain0.00.0
171210MBMidbrain100.0100.0
171281MYMedulla0.00.0
171210MYMedulla82.114204406738387.4814224243164
171281OLFOlfactory bulb0.00.0
171210OLFOlfactory bulb100.0100.0
171281PPons0.00.0
171210PPons80.954956054687580.1272659301758
171281PALPallidum0.00.0
171210PALPallidum99.379364013671997.7687835693359
171281RHPRetrohippocampal region0.00.0
171210RHPRetrohippocampal region100.0100.0
171281sAMYStriatum-like amygdalar nuclei0.00.0
171210sAMYStriatum-like amygdalar nuclei100.0100.0
171281STRStriatum0.00.0
171210STRStriatum100.0100.0
171281STRdStriatum dorsal region0.00.0
171210STRdStriatum dorsal region100.0100.0
171281STRvStriatum ventral region0.00.0
171210STRvStriatum ventral region100.0100.0
171281THThalamus0.00.0
171210THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10965GO:0004759IEAFunctionserine esterase activity
10965GO:0005777NASComponentperoxisome
10965GO:0006629IEAProcesslipid metabolism
10965GO:0006637NASProcessacyl-CoA metabolism
10965GO:0016290IEAFunctionpalmitoyl-CoA hydrolase activity
10965GO:0016291NASFunctionacyl-CoA thioesterase activity
10965GO:0016787IEAFunctionhydrolase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10965ACOT2_HUMANP49753IPR006862Bile_hyd_transAcyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
10965ACOT2_HUMANP49753IPR000379Ser_estrsEsterase/lipase/thioesterase

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