Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10971
Official Symbol:YWHAQ
Other Aliases:1C5|HS1
See related:HGNC:12854|MIM:609009|HPRD:00886
Chromosome:2
Location:2p25.1
Gene Description:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0960
ORGANISM:human
Entrez Gene ID:10971
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.1 :: 1.1 :: 1.7 :: 1.4
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10971GO:0000074NRProcessregulation of progression through cell cycle
10971GO:0006887NRProcessexocytosis
10971GO:0008426NRFunctionprotein kinase C inhibitor activity
10971GO:0019904IEAFunctionprotein domain specific binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-28954NP_054731.2RAS-like GTP-binding protein REMHPRD15237
NP_006817.160491AAH07654.1NIF3L1 proteinHPRD10424
NP_006817.123523NP_036427.1calcineurin binding protein 1BIND301698
NP_006817.179084NP_077007.1methylosome protein 50HPRD14387
NP_006817.1147700NP_803136.1kinesin light chain 2-like isoform aHPRD03212
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
109711433T_HUMANP27348IPR00030814-3-314-3-3 protein

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