Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:10972
Official Symbol:TMED10
Other Aliases:P24(DELTA)|TMP21
See related:HGNC:16998|MIM:605406|HPRD:12013
Chromosome:14
Location:14q24.3
Gene Description:transmembrane emp24-like trafficking protein 10 (yeast)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0385
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Downregulated
Fold Change:-2.7 :: -1.2 :: -1.4 :: -1.3 :: -1.7 :: -1.8
KARG Evidence 2
KARG ID:EVIM0453
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1.6 :: -1.8 :: -1.4 :: -2.5 :: -1
KARG Evidence 3
KARG ID:HOT0137
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 4
KARG ID:HOT0274
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 5
KARG ID:HOT0275
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 6
KARG ID:HOT0034
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 7
KARG ID:HOT0136
ORGANISM:human
Entrez Gene ID:10972
Evidence Type:Whole Genome Association
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
68581CBCerebellum0.00.0
68581CTXCerebral cortex0.00.0
68581HIPHippocampal region0.00.0
68581HPFHippocampal formation0.00.0
68581HYHypothalamus0.00.0
68581LSXLateral septal complex0.00.0
68581MBMidbrain0.00.0
68581MYMedulla0.00.0
68581OLFOlfactory bulb0.00.0
68581PPons0.00.0
68581PALPallidum0.00.0
68581RHPRetrohippocampal region0.00.0
68581sAMYStriatum-like amygdalar nuclei0.00.0
68581STRStriatum0.00.0
68581STRdStriatum dorsal region0.00.0
68581STRvStriatum ventral region0.00.0
68581THThalamus0.00.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
10972GO:0005624TASComponentmembrane fraction
10972GO:0005792ISSComponentmicrosome
10972GO:0005793IDAComponentER-Golgi intermediate compartment
10972GO:0005795IEAComponentGolgi stack
10972GO:0005886TASComponentplasma membrane
10972GO:0005887TASComponentintegral to plasma membrane
10972GO:0006886ISSProcessintracellular protein transport
10972GO:0006888IEAProcessER to Golgi vesicle-mediated transport
10972GO:0006903ISSProcessvesicle targeting
10972GO:0042589ISSComponentzymogen granule membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
10972TMEDA_HUMANP49755IPR009038GOLDGOLD

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