Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:11163
Official Symbol:NUDT4
Other Aliases:DIPP2|DIPP2alpha|DIPP2beta|DKFZp686I1281|HDCMB47P|KIAA0487
See related:HGNC:8051|MIM:609229|HPRD:14850
Chromosome:12
Location:12q21
Gene Description:nudix (nucleoside diphosphate linked moiety X)-type motif 4
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0069
ORGANISM:human
Entrez Gene ID:11163
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:71207
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
71207CBCerebellum26.83126258850144.5944995880127
71207CTXCerebral cortex100.0100.0
71207HIPHippocampal region32.009516716003438.5438222885132
71207HPFHippocampal formation44.713073730468850.0706443786621
71207HYHypothalamus48.938661575317447.1332406997681
71207LSXLateral septal complex39.985074996948242.589017868042
71207MBMidbrain54.531906127929759.2311992645264
71207MYMedulla58.009424209594787.7833442687988
71207OLFOlfactory bulb65.417766571044969.8672904968262
71207PPons49.809001922607465.3837776184082
71207PALPallidum51.532867431640657.1734676361084
71207RHPRetrohippocampal region67.41785430908267.8950843811035
71207sAMYStriatum-like amygdalar nuclei45.243494033813542.2919216156006
71207STRStriatum27.600538253784225.7960815429688
71207STRdStriatum dorsal region20.791387557983419.4478044509888
71207STRvStriatum ventral region36.689894676208529.8042922019958
71207THThalamus70.94440841674877.7797889709473
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
11163GO:0000287IEAFunctionmagnesium ion binding
11163GO:0005622ISSComponentintracellular
11163GO:0007242ISSProcessintracellular signaling cascade
11163GO:0008486ISSFunctiondiphosphoinositol-polyphosphate diphosphatase activity
11163GO:0009187TASProcesscyclic nucleotide metabolism
11163GO:0016787IEAFunctionhydrolase activity
11163GO:0019722ISSProcesscalcium-mediated signaling
11163GO:0019935ISSProcesscyclic-nucleotide-mediated signaling
11163GO:0030145IEAFunctionmanganese ion binding
11163GO:0046831ISSProcessregulation of RNA export from nucleus
11163GO:0046907ISSProcessintracellular transport
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
11163NUDT4_HUMANQ9NZJ9IPR000086NUDIX_hydrolaseNUDIX hydrolase
11163NUDT4_HUMANQ9NZJ9IPR013683VD10_NViral D10 N-terminal

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