Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:11332
Official Symbol:ACOT7
Other Aliases:ACH1|ACT|BACH|CTE-II|LACH|LACH1|MGC1126|hBACH
See related:HGNC:24157|MIM:602587|HPRD:12517
Chromosome:1
Location:1p36.31-p36.11
Gene Description:acyl-CoA thioesterase 7
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0949
ORGANISM:human
Entrez Gene ID:11332
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:11141048
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.1 :: -1.2 :: 1.4 :: 2.6
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
70025CBCerebellum100.0100.0
70025CTXCerebral cortex100.0100.0
70025HIPHippocampal region100.0100.0
70025HPFHippocampal formation100.0100.0
70025HYHypothalamus100.0100.0
70025LSXLateral septal complex100.0100.0
70025MBMidbrain100.0100.0
70025MYMedulla100.0100.0
70025OLFOlfactory bulb100.0100.0
70025PPons100.0100.0
70025PALPallidum100.0100.0
70025RHPRetrohippocampal region100.0100.0
70025sAMYStriatum-like amygdalar nuclei100.0100.0
70025STRStriatum97.983684539794986.6276245117188
70025STRdStriatum dorsal region80.553253173828165.2250576019287
70025STRvStriatum ventral region100.089.158374786377
70025THThalamus100.0100.0
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
11332GO:0000062TASFunctionacyl-CoA binding
11332GO:0004759IEAFunctionserine esterase activity
11332GO:0005739IEAComponentmitochondrion
11332GO:0006629TASProcesslipid metabolism
11332GO:0016290IEAFunctionpalmitoyl-CoA hydrolase activity
11332GO:0016787IEAFunctionhydrolase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
11332IPR006683Thioestr_supfThioesterase superfamily
11332BACH_HUMANO00154IPR006683Thioestr_supfThioesterase superfamily

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