Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1144
Official Symbol:CHRND
Other Aliases:ACHRD|CMS2A|FCCMS|SCCMS
See related:HGNC:1965|MIM:100720|HPRD:01516
Chromosome:2
Location:2q33-q34
Gene Description:cholinergic receptor, nicotinic, delta
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:QTL0011
ORGANISM:human
Entrez Gene ID:1144
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11447CBCerebellum28.855363845825246.1919196844101
11447CTXCerebral cortex45.759358346462243.4380775094032
11447HIPHippocampal region18.617811143398324.3816299438477
11447HPFHippocampal formation26.918708264827729.6956399232149
11447HYHypothalamus5.414962410926824.2357537150383
11447LSXLateral septal complex2.19704045355321.43144164979458
11447MBMidbrain7.304122105240826.71499052643776
11447MYMedulla10.1658859252939.65102034807205
11447OLFOlfactory bulb34.255007505416936.1011079549789
11447PPons7.789401650428777.47006374597549
11447PALPallidum7.626193076372157.96793172508478
11447RHPRetrohippocampal region38.158263325691235.2766441404819
11447sAMYStriatum-like amygdalar nuclei11.36295735836039.28815495967865
11447STRStriatum21.294661641120917.4272775053978
11447STRdStriatum dorsal region26.236202597618121.5740121752024
11447STRvStriatum ventral region15.664452612400113.3997605741024
11447THThalamus10.67263638973248.89061486721039
KARG Evidence 2
KARG ID:QTL0011
Trait:cocaine related behavior
Peak:52.3
Peak Marker:Chrng
Parents:BXD/Ty (B = C57BL/6, D = DBA/2) recombinant inbred
Evidence ID:10591541
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1144GO:0004889TASFunctionnicotinic acetylcholine-activated cation-selective channel activity
1144GO:0005216IEAFunctionion channel activity
1144GO:0005230IEAFunctionextracellular ligand-gated ion channel activity
1144GO:0005892TASComponentnicotinic acetylcholine-gated receptor-channel complex
1144GO:0006811IEAProcession transport
1144GO:0006936TASProcessmuscle contraction
1144GO:0007165TASProcesssignal transduction
1144GO:0015464NRFunctionacetylcholine receptor activity
1144GO:0016021IEAComponentintegral to membrane
1144GO:0045211IEAComponentpostsynaptic membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1144ACHD_HUMANQ07001IPR006201Neur_channelNeurotransmitter-gated ion-channel
1144ACHD_HUMANQ07001IPR006202Neur_chan_lig_bdNeurotransmitter-gated ion-channel ligand-binding
1144ACHD_HUMANQ07001IPR006029Neu_channel_TMNeurotransmitter-gated ion-channel transmembrane region
1144ACHD_HUMANQ07001IPR002394Nic_ach_rcptNicotinic acetylcholine receptor

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