Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1145
Official Symbol:CHRNE
Other Aliases:ACHRE|CMS1D|CMS1E|CMS2A|FCCMS|SCCMS
See related:HGNC:1966|MIM:100725|HPRD:00008
Chromosome:17
Location:17p13-p12
Gene Description:cholinergic receptor, nicotinic, epsilon
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0226
ORGANISM:human
Entrez Gene ID:1145
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:11448
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11448CBCerebellum1.912701189517972.51017433404922
11448CTXCerebral cortex1.337294891476631.63900922983885
11448HIPHippocampal region0.4362751245498660.52295383438468
11448HPFHippocampal formation0.9552018642425540.711039066314697
11448HYHypothalamus0.2399688735604290.208281505852938
11448LSXLateral septal complex0.9036189019680020.508914649486542
11448MBMidbrain0.6138303279876710.86257466673851
11448MYMedulla2.251464486122132.21602308750153
11448OLFOlfactory bulb1.561685562133791.02990953624249
11448PPons1.312618136405941.49812436103821
11448PALPallidum0.1564372405409810.300040453672409
11448RHPRetrohippocampal region1.461944609880450.862460613250732
11448sAMYStriatum-like amygdalar nuclei0.273300327360630.344593644142151
11448STRStriatum0.2979958057403560.222946830093861
11448STRdStriatum dorsal region0.1794234663248060.154622137546539
11448STRvStriatum ventral region0.4408921152353290.293646983802319
11448THThalamus1.067208103835581.57681773602962
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1145GO:0004889TASFunctionnicotinic acetylcholine-activated cation-selective channel activity
1145GO:0005216IEAFunctionion channel activity
1145GO:0005230IEAFunctionextracellular ligand-gated ion channel activity
1145GO:0005892TASComponentnicotinic acetylcholine-gated receptor-channel complex
1145GO:0006811IEAProcession transport
1145GO:0006936TASProcessmuscle contraction
1145GO:0007165TASProcesssignal transduction
1145GO:0007271TASProcesssynaptic transmission, cholinergic
1145GO:0008324TASFunctioncation transporter activity
1145GO:0015464TASFunctionacetylcholine receptor activity
1145GO:0045211IEAComponentpostsynaptic membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1145ACHE_HUMANQ04844IPR006201Neur_channelNeurotransmitter-gated ion-channel
1145ACHE_HUMANQ04844IPR006202Neur_chan_lig_bdNeurotransmitter-gated ion-channel ligand-binding
1145ACHE_HUMANQ04844IPR006029Neu_channel_TMNeurotransmitter-gated ion-channel transmembrane region
1145ACHE_HUMANQ04844IPR002394Nic_ach_rcptNicotinic acetylcholine receptor

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.