Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:114569
Official Symbol:MAL2
Other Aliases:-
See related:HGNC:13634|MIM:609684|HPRD:14351
Chromosome:8
Location:8q23
Gene Description:mal, T-cell differentiation protein 2
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0074
ORGANISM:human
Entrez Gene ID:114569
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.90 :: 0.25 :: 0.64 :: 0.69 :: 1.29 :: -0.39 :: -0.04 :: 0.48 :: -0.02 :: 0.58
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
105853CBCerebellum9.5143961608409910.1115335226059
105853CTXCerebral cortex87.104110717773486.4291763305664
105853HIPHippocampal region49.848680496215881.7198867797852
105853HPFHippocampal formation59.346628189086981.4940853118896
105853HYHypothalamus5.864790380001074.90440583229065
105853LSXLateral septal complex7.925809860229496.84488832950592
105853MBMidbrain8.555454730987558.70674920082092
105853MYMedulla7.597821474075327.94566410779953
105853OLFOlfactory bulb48.787991523742753.5463171005249
105853PPons7.877748012542727.61788582801819
105853PALPallidum7.112878501415256.13286572694778
105853RHPRetrohippocampal region72.129377365112381.3997077941895
105853sAMYStriatum-like amygdalar nuclei8.398317515850077.07915264368057
105853STRStriatum14.032047986984311.1727327108383
105853STRdStriatum dorsal region17.703451871871914.1333563327789
105853STRvStriatum ventral region7.758897930383685.98748549818993
105853THThalamus14.387139558792114.5631551742554
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
114569GO:0005515IPIFunctionprotein binding
114569GO:0016020IEAComponentmembrane
114569GO:0016021IEAComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
114569MAL2_HUMANQ969L2IPR008253MarvelMarvel

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