Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1152
Official Symbol:CKB
Other Aliases:B-CK|CKBB
See related:HGNC:1991|MIM:123280|HPRD:00423
Chromosome:14
Location:14q32
Gene Description:creatine kinase, brain
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0499
ORGANISM:human
Entrez Gene ID:1152
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24264
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIP0197
ORGANISM:human
Entrez Gene ID:1152
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:15542695
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Whole Brain
Drug Effects:Upregulated
Fold Change:2.00
KARG Evidence 3
KARG ID:EVIP0213
ORGANISM:human
Entrez Gene ID:1152
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:15542695
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Whole Brain
Drug Effects:Downregulated
Fold Change:0.29
KARG Evidence 4
KARG ID:EVIP0257
ORGANISM:human
Entrez Gene ID:1152
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:16172612
Addiction Drug:ALCOHOL
Addiction Drug Detail:Chronic alcohol use
Addiction Brain Area:Brain
Drug Effects:Downregulated
Fold Change:-1.1::-1.4
KARG Evidence 5
KARG ID:QTL0194
ORGANISM:human
Entrez Gene ID:1152
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
KARG Evidence 6
KARG ID:QTL0194
Trait:METH responses for home cage activity, body temperature
Peak:55
Peak Marker:Xmmv50
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:8987796
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1152GO:0004111TASFunctioncreatine kinase activity
1152GO:0005737NRComponentcytoplasm
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-1158NP_001815.2muscle creatine kinaseHPRD00426
NP_001814.21158-Creatine kinase muscle typeHPRD00423
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1152KCRB_HUMANP12277IPR000749ATP-gua_PtransATP:guanido phosphotransferase

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