Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:116
Official Symbol:ADCYAP1
Other Aliases:MGC126852|PACAP
See related:HGNC:241|MIM:102980|HPRD:02369
Chromosome:18
Location:18p11
Gene Description:adenylate cyclase activating polypeptide 1 (pituitary)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0287
ORGANISM:human
Entrez Gene ID:116
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:11516
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11516CBCerebellum15.933106422424324.7629222869873
11516CTXCerebral cortex39.458515167236343.1926422119141
11516HIPHippocampal region6.1028919219970713.5872106552124
11516HPFHippocampal formation9.3328976631164614.5044088363647
11516HYHypothalamus54.11502647399981.2597732543945
11516LSXLateral septal complex1.121251985430721.18372845649719
11516MBMidbrain31.697767257690439.141637802124
11516MYMedulla22.37058448791532.1499395370483
11516OLFOlfactory bulb30.588801383972242.9406070709229
11516PPons23.121973037719730.7101821899414
11516PALPallidum4.509952187538156.51417374610901
11516RHPRetrohippocampal region14.083373069763215.7035036087036
11516sAMYStriatum-like amygdalar nuclei20.527346611022927.7440481185913
11516STRStriatum2.790966510772713.62279033660889
11516STRdStriatum dorsal region0.4247084110975270.418538972735405
11516STRvStriatum ventral region1.587547719478612.0374521613121
11516THThalamus11.503596782684315.1549906730652
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
116GO:0005179IEAFunctionhormone activity
116GO:0005184TASFunctionneuropeptide hormone activity
116GO:0005576IEAComponentextracellular region
116GO:0005625TASComponentsoluble fraction
116GO:0007190TASProcessadenylate cyclase activation
116GO:0007267TASProcesscell-cell signaling
116GO:0007565TASProcesspregnancy
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001108.1117BAA04466.1PACAP receptorHPRD00045
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
116PACA_HUMANP18509IPR000532GlucagonGlucagon/GIP/secretin/VIP

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