Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1269
Official Symbol:CNR2
Other Aliases:CB2|CX5
See related:HGNC:2160|MIM:605051|HPRD:05444
Chromosome:1
Location:1p36.11
Gene Description:cannabinoid receptor 2 (macrophage)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0510
ORGANISM:human
Entrez Gene ID:1269
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:57302
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12802CBCerebellum2.462114155292511.91030877828598
12802CTXCerebral cortex8.203386902809145.26338249444962
12802HIPHippocampal region7.400586366653444.28109419345856
12802HPFHippocampal formation8.610085606575015.89501345157623
12802HYHypothalamus7.034981012344363.947833776474
12802LSXLateral septal complex1.69975069165230.918768972158432
12802MBMidbrain2.146545469760891.6805100440979
12802MYMedulla3.740608692169192.64956516027451
12802OLFOlfactory bulb26.482797622680715.3371078968048
12802PPons2.925594449043272.1371066570282
12802PALPallidum1.865046083927151.07786753773689
12802RHPRetrohippocampal region9.928133785724647.35736209154129
12802sAMYStriatum-like amygdalar nuclei16.08117043972029.25778663158417
12802STRStriatum4.845974266529082.61484143137932
12802STRdStriatum dorsal region2.534852802753451.30856114625931
12802STRvStriatum ventral region8.701873898506164.30577226728201
12802THThalamus2.773155748844151.59200268983841
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1269GO:0004872IEAFunctionreceptor activity
1269GO:0004949TASFunctioncannabinoid receptor activity
1269GO:0005886TASComponentplasma membrane
1269GO:0005887TASComponentintegral to plasma membrane
1269GO:0006955TASProcessimmune response
1269GO:0007165IEAProcesssignal transduction
1269GO:0007187TASProcessG-protein signaling, coupled to cyclic nucleotide second messenger
1269GO:0007610TASProcessbehavior
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001832.1---BIND183020
NP_001832.1---BIND183024
NP_001832.1---BIND183023
NP_001832.1---BIND183021
NP_001832.1---BIND183022
NP_001832.12769NP_002059.1guanine nucleotide binding protein (G protein), alpha 15 (Gq class)HPRD00760
NP_001832.12769NP_002059.1guanine nucleotide binding protein (G protein), alpha 15 (Gq class)HPRD05444
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1269CNR2_HUMANP34972IPR001551Canbinoid_rcpt_2Cannabinoid receptor, type 2
1269CNR2_HUMANP34972IPR002230Cnbnoid_rcptCannabinoid receptor
1269CNR2_HUMANP34972IPR000276GPCR_RhodpsnRhodopsin-like GPCR superfamily

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.