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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry

For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information Gene ID: 1282 Official Symbol: COL4A1 Other Aliases: arresten See related: HGNC:2202|MIM:120130|HPRD:00359 Chromosome: 13 Location: 13q34 Gene Description: collagen, type IV, alpha 1 Gene type: protein-coding Gene Structure: Genomic Context: KARG Evidence 1 KARG ID: EVIM0337 ORGANISM: human Entrez Gene ID: 1282 Evidence Type: Microarray Evidence ID Type: PUBMED Evidence ID: 15816859 Addiction Drug: ALCOHOL Addiction Drug Detail: ALCOHOL ABUSE Addiction Brain Area: Nucleus Accumbens Drug Effects: Downregulated Fold Change: -0.56 Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas) Mouse Entrez Gene ID Brain Region Brain Region Detail Expression Level Expression Density Gene Ontology Gene ID GO ID Evidence GO Type GO Description 1282 GO:0005201 IEA Function extracellular matrix structural constituent 1282 GO:0005581 IEA Component collagen 1282 GO:0005587 NR Component collagen type IV 1282 GO:0005737 IEA Component cytoplasm 1282 GO:0006817 IEA Process phosphate transport Interaction Information Gene Product ID Interactant Gene ID Interactant Gene Product ID Interactant Gene Product Name Source Source ID - 1294 NP_000085.1 alpha 1 type VII collagen precursor HPRD 00358 - 1284 NP_001837.1 alpha 2 type IV collagen preproprotein HPRD 00355 - 2335 NP_002017.1 fibronectin 1 isoform 3 preproprotein HPRD 00626 NP_001836.1 - - Galactolectin HPRD 00359 NP_001836.1 - - Oxidised Low Density lipoprotein HPRD 00359 NP_001836.1 1294 - Collagen, type VII, alpha 1 HPRD 00359 NP_001836.1 6288 NP_000322.2 serum amyloid A1 isoform 1 HPRD 00097 NP_001836.1 6288 NP_000322.2 serum amyloid A1 isoform 1 HPRD 00359 NP_001836.1 7045 NP_000349.1 transforming growth factor, beta-induced, 68kDa HPRD 00359 NP_001836.1 7045 NP_000349.1 transforming growth factor, beta-induced, 68kDa HPRD 03409 NP_001836.1 1282 NP_001836.1 alpha 1 type IV collagen preproprotein HPRD 00359 NP_001836.1 1284 NP_001837.1 alpha 2 type IV collagen preproprotein HPRD 00359 NP_001836.1 1634 NP_001911.1 decorin isoform a preproprotein HPRD 00501 NP_001836.1 1634 NP_001911.1 decorin isoform a preproprotein HPRD 00359 NP_001836.1 2199 NP_001989.1 fibulin 2 precursor HPRD 00630 NP_001836.1 2199 NP_001989.1 fibulin 2 precursor HPRD 00359 NP_001836.1 2335 NP_002017.1 fibronectin 1 isoform 3 preproprotein HPRD 00626 NP_001836.1 2335 NP_002017.1 fibronectin 1 isoform 3 preproprotein HPRD 00359 NP_001836.1 4147 NP_002371.2 matrilin 2 precursor HPRD 03660 NP_001836.1 4147 NP_002371.2 matrilin 2 precursor HPRD 00359 NP_001836.1 3026 NP_004123.1 hyaluronan binding protein 2 HPRD 00359 NP_001836.1 3026 NP_004123.1 hyaluronan binding protein 2 HPRD 04890 NP_001836.1 4318 NP_004985.1 matrix metalloproteinase 9 preproprotein HPRD 00359 NP_001836.1 4318 NP_004985.1 matrix metalloproteinase 9 preproprotein HPRD 00387 NP_001836.1 5270 NP_006207.1 plasminogen activator inhibitor type 1, member 2 HPRD 00359 NP_001836.1 22918 NP_036204.1 complement component 1, q subcomponent, receptor 1 HPRD 00396 NP_001836.1 22918 NP_036204.1 complement component 1, q subcomponent, receptor 1 HPRD 00359 NP_001836.1 5008 NP_065391.1 oncostatin M precursor HPRD 01300 NP_001836.1 5008 NP_065391.1 oncostatin M precursor HPRD 00359 Domain Information Gene ID Uniprot/Swissprot ID Uniprot/Swissprot ACC Interpro ID Interpro Short Description Interpro Long Description 1282 CO4A1_HUMAN P02462 IPR008160 Collagen Collagen triple helix repeat 1282 CO4A1_HUMAN P02462 IPR009765 Pericardin_rpt Pericardin like 1282 CO4A1_HUMAN P02462 IPR001442 Procollagn4_C Type 4 procollagen, C-terminal repeat 1282 CO4A1_HUMAN P02462 IPR000694 PRO_rich Proline-rich region © Center for Bioinformatics(CBI), Peking University Any Comments and suggestions to : KARG GROUP.