Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1282
Official Symbol:COL4A1
Other Aliases:arresten
See related:HGNC:2202|MIM:120130|HPRD:00359
Chromosome:13
Location:13q34
Gene Description:collagen, type IV, alpha 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0337
ORGANISM:human
Entrez Gene ID:1282
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:-0.56
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1282GO:0005201IEAFunctionextracellular matrix structural constituent
1282GO:0005581IEAComponentcollagen
1282GO:0005587NRComponentcollagen type IV
1282GO:0005737IEAComponentcytoplasm
1282GO:0006817IEAProcessphosphate transport
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-1294NP_000085.1alpha 1 type VII collagen precursorHPRD00358
-1284NP_001837.1alpha 2 type IV collagen preproproteinHPRD00355
-2335NP_002017.1fibronectin 1 isoform 3 preproproteinHPRD00626
NP_001836.1--GalactolectinHPRD00359
NP_001836.1--Oxidised Low Density lipoproteinHPRD00359
NP_001836.11294-Collagen, type VII, alpha 1HPRD00359
NP_001836.16288NP_000322.2serum amyloid A1 isoform 1HPRD00097
NP_001836.16288NP_000322.2serum amyloid A1 isoform 1HPRD00359
NP_001836.17045NP_000349.1transforming growth factor, beta-induced, 68kDaHPRD00359
NP_001836.17045NP_000349.1transforming growth factor, beta-induced, 68kDaHPRD03409
NP_001836.11282NP_001836.1alpha 1 type IV collagen preproproteinHPRD00359
NP_001836.11284NP_001837.1alpha 2 type IV collagen preproproteinHPRD00359
NP_001836.11634NP_001911.1decorin isoform a preproproteinHPRD00501
NP_001836.11634NP_001911.1decorin isoform a preproproteinHPRD00359
NP_001836.12199NP_001989.1fibulin 2 precursorHPRD00630
NP_001836.12199NP_001989.1fibulin 2 precursorHPRD00359
NP_001836.12335NP_002017.1fibronectin 1 isoform 3 preproproteinHPRD00626
NP_001836.12335NP_002017.1fibronectin 1 isoform 3 preproproteinHPRD00359
NP_001836.14147NP_002371.2matrilin 2 precursorHPRD03660
NP_001836.14147NP_002371.2matrilin 2 precursorHPRD00359
NP_001836.13026NP_004123.1hyaluronan binding protein 2HPRD00359
NP_001836.13026NP_004123.1hyaluronan binding protein 2HPRD04890
NP_001836.14318NP_004985.1matrix metalloproteinase 9 preproproteinHPRD00359
NP_001836.14318NP_004985.1matrix metalloproteinase 9 preproproteinHPRD00387
NP_001836.15270NP_006207.1plasminogen activator inhibitor type 1, member 2HPRD00359
NP_001836.122918NP_036204.1complement component 1, q subcomponent, receptor 1HPRD00396
NP_001836.122918NP_036204.1complement component 1, q subcomponent, receptor 1HPRD00359
NP_001836.15008NP_065391.1oncostatin M precursorHPRD01300
NP_001836.15008NP_065391.1oncostatin M precursorHPRD00359
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1282CO4A1_HUMANP02462IPR008160CollagenCollagen triple helix repeat
1282CO4A1_HUMANP02462IPR009765Pericardin_rptPericardin like
1282CO4A1_HUMANP02462IPR001442Procollagn4_CType 4 procollagen, C-terminal repeat
1282CO4A1_HUMANP02462IPR000694PRO_richProline-rich region

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