Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1291
Official Symbol:COL6A1
Other Aliases:OPLL
See related:HGNC:2211|MIM:120220|HPRD:00370
Chromosome:21
Location:21q22.3
Gene Description:collagen, type VI, alpha 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0116
ORGANISM:human
Entrez Gene ID:1291
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:12833
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12833CBCerebellum35.207753181457544.5555438995361
12833CTXCerebral cortex82.076812744140684.7911643981934
12833HIPHippocampal region47.980504035949753.839093208313
12833HPFHippocampal formation50.51539897918754.8593235015869
12833HYHypothalamus45.587374687194837.1013689041138
12833LSXLateral septal complex74.153852462768675.8081378936768
12833MBMidbrain32.564785957336430.1954917907715
12833MYMedulla49.633992195129450.2136764526367
12833OLFOlfactory bulb100.0100.0
12833PPons50.803497314453148.6972217559814
12833PALPallidum55.9819335937571.5144004821777
12833RHPRetrohippocampal region52.388904571533252.6858348846436
12833sAMYStriatum-like amygdalar nuclei88.410545349121196.9015655517578
12833STRStriatum100.0100.0
12833STRdStriatum dorsal region95.992565155029393.1340293884277
12833STRvStriatum ventral region100.0100.0
12833THThalamus17.303939104080215.3233551979065
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1291GO:0005201IEAFunctionextracellular matrix structural constituent
1291GO:0005515IEAFunctionprotein binding
1291GO:0005554NDFunctionmolecular function unknown
1291GO:0005581IEAComponentcollagen
1291GO:0005589NASComponentcollagen type VI
1291GO:0005737IEAComponentcytoplasm
1291GO:0006817IEAProcessphosphate transport
1291GO:0007155IEAProcesscell adhesion
1291GO:0007155NASProcesscell adhesion
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-3912NP_002282.1laminin, beta 1 precursorHPRD01029
NP_001839.13912-Laminin beta 1HPRD00370
NP_001839.13959NP_005558.1galectin 3 binding proteinHPRD00370
NP_001839.13959NP_005558.1galectin 3 binding proteinHPRD02796
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1291CO6A1_HUMANP12109IPR008160CollagenCollagen triple helix repeat
1291CO6A1_HUMANP12109IPR000694PRO_richProline-rich region
1291CO6A1_HUMANP12109IPR013694VITVault protein inter-alpha-trypsin
1291CO6A1_HUMANP12109IPR013608VWA_NVWA N-terminal
1291CO6A1_HUMANP12109IPR002035VWF_Avon Willebrand factor, type A

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