Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1346
Official Symbol:COX7A1
Other Aliases:COX7A|COX7AH|COX7AM
See related:HGNC:2287|MIM:123995|HPRD:00481
Chromosome:19
Location:19q13.1
Gene Description:cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0271
ORGANISM:human
Entrez Gene ID:1346
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Downregulated
Fold Change:-0.74
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12865CBCerebellum0.3807076811790470.653247714042664
12865CTXCerebral cortex0.4657210111618040.699857294559479
12865HIPHippocampal region0.2499665170907970.27978041768074
12865HPFHippocampal formation0.2111897915601730.222541570663452
12865HYHypothalamus0.0476424582302570.148332044482231
12865LSXLateral septal complex0.00.0
12865MBMidbrain0.09288989007472990.222481891512871
12865MYMedulla0.5905839800834660.71768456697464
12865OLFOlfactory bulb1.039417386054991.51147568225861
12865PPons0.1220979765057560.303160607814789
12865PALPallidum0.1117319688200950.158184587955475
12865RHPRetrohippocampal region0.1422842741012570.123543873429298
12865sAMYStriatum-like amygdalar nuclei0.1598822921514510.17233219742775
12865STRStriatum0.1427904814481740.194693699479103
12865STRdStriatum dorsal region0.1793906390666960.282134205102921
12865STRvStriatum ventral region0.1144740581512450.103205300867558
12865THThalamus0.1645792275667190.834854423999786
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1346GO:0004129TASFunctioncytochrome-c oxidase activity
1346GO:0005739TASComponentmitochondrion
1346GO:0006118IEAProcesselectron transport
1346GO:0016020IEAComponentmembrane
1346GO:0016021IEAComponentintegral to membrane
1346GO:0016491IEAFunctionoxidoreductase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1346CX7A1_HUMANP24310IPR003177COX7aCytochrome c oxidase, subunit VIIa

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