Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1407
Official Symbol:CRY1
Other Aliases:PHLL1
See related:HGNC:2384|MIM:601933|HPRD:09050
Chromosome:12
Location:12q23-q24.1
Gene Description:cryptochrome 1 (photolyase-like)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0149
ORGANISM:human
Entrez Gene ID:1407
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:12952
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12952CBCerebellum1.113439917564391.64923822879791
12952CTXCerebral cortex0.3913366198539730.478908658027649
12952HIPHippocampal region1.098355650901791.13166654109955
12952HPFHippocampal formation0.7767226099967960.907470405101776
12952HYHypothalamus0.0421759672462940.141322702169418
12952LSXLateral septal complex0.1421224623918530.164674893021584
12952MBMidbrain0.1624346822500230.440363824367523
12952MYMedulla0.1487267315387730.295245587825775
12952OLFOlfactory bulb0.9416663050651551.86060786247253
12952PPons0.04008834064006810.0652025789022446
12952PALPallidum0.08513938635587690.17062996327877
12952RHPRetrohippocampal region0.2088400423526760.381677657365799
12952sAMYStriatum-like amygdalar nuclei0.09156421571969990.255429834127426
12952STRStriatum0.1248743608593940.17445333302021
12952STRdStriatum dorsal region0.1274702996015550.150190651416779
12952STRvStriatum ventral region0.1069578677415850.186325788497925
12952THThalamus0.1963521391153340.214492619037628
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1407GO:0003677TASFunctionDNA binding
1407GO:0003913IEAFunctionDNA photolyase activity
1407GO:0005739TASComponentmitochondrion
1407GO:0006281IEAProcessDNA repair
1407GO:0007601NRProcessvisual perception
1407GO:0007623TASProcesscircadian rhythm
1407GO:0008020TASFunctionG-protein coupled photoreceptor activity
1407GO:0016829IEAFunctionlyase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-8863NP_058515.1period 3HPRD09138
NP_004066.18863-Period circadian protein 3HPRD09050
NP_004066.18914-TIM1HPRD09050
NP_004066.11454-Casein kinase 1, epsilonHPRD09050
NP_004066.15187NP_002607.1period 1HPRD09050
NP_004066.18864NP_073728.1period 2 isoform 1HPRD09050
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1407IPR006050DNA_photolyase_NDNA photolyase, N-terminal
1407IPR005101Photolyse_FAD_bdDNA photolyase, FAD-binding

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