Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1428
Official Symbol:CRYM
Other Aliases:DFNA40|THBP
See related:HGNC:2418|MIM:123740|HPRD:08831
Chromosome:16
Location:16p13.11-p12.3
Gene Description:crystallin, mu
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0363
ORGANISM:human
Entrez Gene ID:1428
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Frontal Cortex
Drug Effects:Upregulated
Fold Change:1.7 :: 1.4 :: 1.9 :: 1.1 :: -1.2 :: -1.4
KARG Evidence 2
KARG ID:EVIM0431
ORGANISM:human
Entrez Gene ID:1428
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:12065639
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Motor Cortex
Drug Effects:Downregulated
Fold Change:-1.2 :: -1.3 :: -2.5 :: 1.1 :: -1.2
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
12971CBCerebellum4.268697977066046.82308828830719
12971CTXCerebral cortex71.684597015380985.4230690002441
12971HIPHippocampal region100.0100.0
12971HPFHippocampal formation100.0100.0
12971HYHypothalamus3.649526834487924.76340746879578
12971LSXLateral septal complex33.490769386291560.7724199295044
12971MBMidbrain2.526404201984413.14083647727966
12971MYMedulla1.781559675931932.29363782703876
12971OLFOlfactory bulb58.996088027954177.0243949890137
12971PPons2.937279209494593.11765605211258
12971PALPallidum15.176542520523122.1943755149841
12971RHPRetrohippocampal region100.0100.0
12971sAMYStriatum-like amygdalar nuclei35.360552787780846.3808851242065
12971STRStriatum68.195341110229579.2471599578857
12971STRdStriatum dorsal region52.501861572265661.1067218780518
12971STRvStriatum ventral region100.0100.0
12971THThalamus8.538998603820813.8999650478363
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1428GO:0003824IEAFunctioncatalytic activity
1428GO:0007601TASProcessvisual perception
1428GO:0008473TASFunctionornithine cyclodeaminase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1428CRYM_HUMANQ14894IPR003462ODC_Mu_crystallOrnithine cyclodeaminase/mu-crystallin
1428CRYM_HUMANQ14894IPR006151Shikimate_DHShikimate/quinate 5-dehydrogenase

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