Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:14810
Official Symbol:Grin1
Other Aliases:GluRdelta1|NMDAR1|NR1|Nmdar
See related:MGI:95819
Chromosome:2
Location:2 A3|2 12.0 cM
Gene Description:glutamate receptor, ionotropic, NMDA1 (zeta 1)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC1798
ORGANISM:mouse
Entrez Gene ID:14810
Evidence Type:Mapping from human
Evidence ID Type:Entrez Gene
Evidence ID:2902
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIL0172
ORGANISM:mouse
Entrez Gene ID:14810
Evidence Type:LT Reports
Evidence ID Type:PUBMED
Evidence ID:15967985
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE REWARD
Addiction Brain Area:Ventral Tegmental Area
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
14810GO:0000287IEAFunctionmagnesium ion binding
14810GO:0004872IEAFunctionreceptor activity
14810GO:0004970IEAFunctionionotropic glutamate receptor activity
14810GO:0005102IDAFunctionreceptor binding
14810GO:0005215IEAFunctiontransporter activity
14810GO:0005216IEAFunctionion channel activity
14810GO:0005234IEAFunctionglutamate-gated ion channel activity
14810GO:0005267RCAFunctionpotassium channel activity
14810GO:0005509IEAFunctioncalcium ion binding
14810GO:0005515IPIFunctionprotein binding
14810GO:0005624IDAComponentmembrane fraction
14810GO:0005737IDAComponentcytoplasm
14810GO:0006810IEAProcesstransport
14810GO:0006811IEAProcession transport
14810GO:0006813RCAProcesspotassium ion transport
14810GO:0007268TASProcesssynaptic transmission
14810GO:0008021IDAComponentsynaptic vesicle
14810GO:0016020IEAComponentmembrane
14810GO:0016021IEAComponentintegral to membrane
14810GO:0045202ISSComponentsynapse
14810GO:0045211IDAComponentpostsynaptic membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
14810NMDZ1_MOUSEP35438IPR001828ANF_lig_bd_rcptExtracellular ligand-binding receptor
14810NMDZ1_MOUSEP35438IPR001311glu_rcpt_sol_bdSolute-binding protein/glutamate receptor
14810NMDZ1_MOUSEP35438IPR000337GPCR_MgrGPCR, family 3, metabotropic glutamate receptor-like
14810NMDZ1_MOUSEP35438IPR001320Iontro_glu_rcptIonotropic glutamate receptor
14810NMDZ1_MOUSEP35438IPR001622K+channel_poreK+ channel, pore region
14810NMDZ1_MOUSEP35438IPR001508NMDA_rcptNMDA receptor

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