Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1548
Official Symbol:CYP2A6
Other Aliases:CPA6|CYP2A|CYP2A3|P450C2A|P450PB
See related:HGNC:2610|MIM:122720|HPRD:00420
Chromosome:19
Location:19q13.2
Gene Description:cytochrome P450, family 2, subfamily A, polypeptide 6
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIL0201
ORGANISM:human
Entrez Gene ID:1548
Evidence Type:LT Reports
Evidence ID Type:PUBMED
Evidence ID:16141602
Addiction Drug:NICOTINE
Addiction Drug Detail:NICOTINE ABUSE
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVID0007
ORGANISM:human
Entrez Gene ID:1548
Evidence Type:Database Annotations
Evidence ID Type:OMIM
Evidence ID:MIM:122720
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1548GO:0005506IEAFunctioniron ion binding
1548GO:0005783IEAComponentendoplasmic reticulum
1548GO:0005792TASComponentmicrosome
1548GO:0006118IEAProcesselectron transport
1548GO:0008389TASFunctioncoumarin 7-hydroxylase activity
1548GO:0016020IEAComponentmembrane
1548GO:0019825TASFunctionoxygen binding
1548GO:0020037IEAFunctionheme binding
1548GO:0046872IEAFunctionmetal ion binding
1548GO:0050381IEAFunctionunspecific monooxygenase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000753.2---BIND262272
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1548CP2A6_HUMANP11509IPR002397BP450B-class P450
1548CP2A6_HUMANP11509IPR001128Cytochrome_P450Cytochrome P450
1548CP2A6_HUMANP11509IPR002401EP450IE-class P450, group I
1548CP2A6_HUMANP11509IPR002403EP450IVE-class P450, group IV
1548CP2A6_HUMANP11509IPR008067EP450_CYP2AE-class P450, CYP2A
1548CP2A6_HUMANP11509IPR008068EP450_CYP2BE-class P450, CYP2B
1548CP2A6_HUMANP11509IPR008069EP450_CYP2DE-class P450, CYP2D

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