Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:158
Official Symbol:ADSL
Other Aliases:-
See related:HGNC:291|MIM:608222|HPRD:00049
Chromosome:22
Location:22q13.1|22q13.2
Gene Description:adenylosuccinate lyase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0133
ORGANISM:human
Entrez Gene ID:158
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:11564
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11564CBCerebellum7.2859883308410610.2593507766724
11564CTXCerebral cortex8.217636108398446.79323816299438
11564HIPHippocampal region9.7988424301147511.4357299804688
11564HPFHippocampal formation9.7335119247436510.2502784729004
11564HYHypothalamus0.1143653094768520.120319366455078
11564LSXLateral septal complex1.476802468299871.65031814575195
11564MBMidbrain0.8863345384597781.61977386474609
11564MYMedulla0.5410943627357480.691004037857056
11564OLFOlfactory bulb3.293579339981083.77267503738403
11564PPons1.648291945457463.16958546638489
11564PALPallidum0.09494175016880040.152773454785347
11564RHPRetrohippocampal region9.862441062927258.83883285522461
11564sAMYStriatum-like amygdalar nuclei0.09024162590503690.0576665885746479
11564STRStriatum0.4474993050098420.622626066207886
11564STRdStriatum dorsal region0.5206356644630430.827048063278198
11564STRvStriatum ventral region0.1920881867408750.172457844018936
11564THThalamus1.151623964309691.86357641220093
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
158GO:0004018TASFunctionadenylosuccinate lyase activity
158GO:0009152IEAProcesspurine ribonucleotide biosynthesis
158GO:0016829IEAFunctionlyase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
158PUR8_HUMANP30566IPR013539ASL_CAdenylosuccinate lyase C-terminal
158PUR8_HUMANP30566IPR003031D_crystallinDelta crystallin
158PUR8_HUMANP30566IPR000362Fumarate_lyaseFumarate lyase

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