Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:159
Official Symbol:ADSS
Other Aliases:ADEH|MGC20404
See related:HGNC:292|MIM:103060|HPRD:00050
Chromosome:1
Location:1cen-q12
Gene Description:adenylosuccinate synthase
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0228
ORGANISM:human
Entrez Gene ID:159
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:11566
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
11566CBCerebellum1.188321590423581.40265870094299
11566CTXCerebral cortex5.169336795806881.59864938259125
11566HIPHippocampal region2.400119781494141.53862154483795
11566HPFHippocampal formation1.846166729927060.997667849063873
11566HYHypothalamus0.195923224091530.0926994830369949
11566LSXLateral septal complex0.00.0
11566MBMidbrain0.8592905998229980.49139791727066
11566MYMedulla5.094265937805182.84569549560547
11566OLFOlfactory bulb2.008460760116580.648338615894318
11566PPons1.411466479301450.702058136463165
11566PALPallidum0.7571886777877810.629645228385925
11566RHPRetrohippocampal region1.071933507919310.396243125200272
11566sAMYStriatum-like amygdalar nuclei0.1520094126462940.111475870013237
11566STRStriatum0.7917768359184270.440671861171722
11566STRdStriatum dorsal region0.6617546081542970.404948741197586
11566STRvStriatum ventral region1.781835079193120.857318937778473
11566THThalamus0.8418329358100890.658568739891052
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
159GO:0000166IEAFunctionnucleotide binding
159GO:0000287IEAFunctionmagnesium ion binding
159GO:0004019IEAFunctionadenylosuccinate synthase activity
159GO:0004019TASFunctionadenylosuccinate synthase activity
159GO:0005525IEAFunctionGTP binding
159GO:0006164IEAProcesspurine nucleotide biosynthesis
159GO:0006167TASProcessAMP biosynthesis
159GO:0016874IEAFunctionligase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001117.1--F-actinHPRD00050
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
159PURA2_HUMANP30520IPR001114Asucc_synthtaseAdenylosuccinate synthetase

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