Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1613
Official Symbol:DAPK3
Other Aliases:FLJ36473|ZIP|ZIPK
See related:HGNC:2676|MIM:603289|HPRD:04478
Chromosome:19
Location:19p13.3
Gene Description:death-associated protein kinase 3
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0132
ORGANISM:human
Entrez Gene ID:1613
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:13144
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13144CBCerebellum4.628002643585214.52455568313599
13144CTXCerebral cortex9.802344322204596.95825910568237
13144HIPHippocampal region11.668205261230511.3407907485962
13144HPFHippocampal formation10.18376445770268.96105003356934
13144HYHypothalamus0.8239456415176390.64887261390686
13144LSXLateral septal complex0.8018023371696470.558426558971405
13144MBMidbrain2.241374731063842.39914846420288
13144MYMedulla4.973840713500986.26254320144653
13144OLFOlfactory bulb4.967871189117434.30578851699829
13144PPons4.197850704193125.05785512924194
13144PALPallidum1.546310067176821.30806815624237
13144RHPRetrohippocampal region7.902693271636965.83968639373779
13144sAMYStriatum-like amygdalar nuclei1.268304228782650.870956778526306
13144STRStriatum1.610923409461981.12060403823853
13144STRdStriatum dorsal region1.628660559654241.1761087179184
13144STRvStriatum ventral region2.419860839843751.49347317218781
13144THThalamus1.861117243766781.5954806804657
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1613GO:0000166IEAFunctionnucleotide binding
1613GO:0004674IDAFunctionprotein serine/threonine kinase activity
1613GO:0005515IPIFunctionprotein binding
1613GO:0005524IDAFunctionATP binding
1613GO:0005634ISSComponentnucleus
1613GO:0006468IDAProcessprotein amino acid phosphorylation
1613GO:0006915IEAProcessapoptosis
1613GO:0006917IMPProcessinduction of apoptosis
1613GO:0007243IDAProcessprotein kinase cascade
1613GO:0016740IEAFunctiontransferase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-26574NP_036270.1apoptosis antagonizing transcription factorHPRD12236
NP_001339.1--AATFHPRD04478
NP_001339.1--PAR4HPRD04478
NP_001339.11613NP_001339.1death-associated protein kinase 3HPRD04478
NP_001339.11616NP_001341.1death-associated protein 6HPRD04424
NP_001339.11616NP_001341.1death-associated protein 6HPRD04478
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1613DAPK3_HUMANO43293IPR013543CaMKII_ADCalcium/calmodulin dependent protein kinase II, association-domain
1613DAPK3_HUMANO43293IPR000719Prot_kinaseProtein kinase
1613DAPK3_HUMANO43293IPR008271Ser_thr_pkin_ASSerine/threonine protein kinase, active site
1613DAPK3_HUMANO43293IPR001245Tyr_pkinaseTyrosine protein kinase
1613DAPK3_HUMANO43293IPR013695WAKWall-associated kinase

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