Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1634
Official Symbol:DCN
Other Aliases:CSCD|DSPG2|PG40|PGII|PGS2|SLRR1B
See related:HGNC:2705|MIM:125255|HPRD:00501
Chromosome:12
Location:12q21.33
Gene Description:decorin
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0377
ORGANISM:human
Entrez Gene ID:1634
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:29139
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13179CBCerebellum19.121891975402852.2594687143962
13179CTXCerebral cortex15.992250045140616.7054131825765
13179HIPHippocampal region23.273616154988650.6063340504964
13179HPFHippocampal formation33.832672119140664.3201154073079
13179HYHypothalamus9.7482224305470817.7288951873779
13179LSXLateral septal complex5.7090976238250713.1160012880961
13179MBMidbrain18.347635587056541.141414642334
13179MYMedulla18.076041221618740.6192665100098
13179OLFOlfactory bulb24.422609488169429.0696887969971
13179PPons15.596837679545133.7507387797038
13179PALPallidum10.837582508722918.2754316329956
13179RHPRetrohippocampal region52.051157633463581.5157318115234
13179sAMYStriatum-like amygdalar nuclei13.596581459045423.0344950358073
13179STRStriatum11.224804878234913.8864121437073
13179STRdStriatum dorsal region11.872179031372113.4128402074178
13179STRvStriatum ventral region10.316637873649611.3743793169657
13179THThalamus13.328351974487326.548625310262
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1634GO:0005578IEAComponentextracellular matrix (sensu Metazoa)
1634GO:0009887TASProcessorgan morphogenesis
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-2200NP_000129.1fibrillin 1HPRD00618
-2006NP_000492.1elastinHPRD00556
-7057NP_003237.1thrombospondin 1HPRD01765
NP_001911.1--WISP-1HPRD00501
NP_001911.17057-Thrombospondin IHPRD00501
NP_001911.12200-Fibrillin 1HPRD00501
NP_001911.12006-ElastinHPRD00501
NP_001911.15320NP_000291.1phospholipase A2, group IIAHPRD00501
NP_001911.15320NP_000291.1phospholipase A2, group IIAHPRD00501
NP_001911.17124NP_000585.1tumor necrosis factor (cachectin)HPRD01855
NP_001911.17124NP_000585.1tumor necrosis factor (cachectin)HPRD00501
NP_001911.17040NP_000651.1transforming growth factor, beta 1HPRD00501
NP_001911.17040NP_000651.1transforming growth factor, beta 1HPRD01821
NP_001911.12316NP_001447.1filamin 1 (actin-binding protein-280)HPRD02060
NP_001911.12316NP_001447.1filamin 1 (actin-binding protein-280)HPRD00501
NP_001911.12335NP_002017.1fibronectin 1 isoform 3 preproproteinHPRD00626
NP_001911.12335NP_002017.1fibronectin 1 isoform 3 preproproteinHPRD00501
NP_001911.16441NP_003010.2surfactant, pulmonary-associated protein DHPRD00501
NP_001911.16441NP_003010.2surfactant, pulmonary-associated protein DHPRD01522
NP_001911.18840NP_003873.1WNT1 inducible signaling pathway protein 1 isoform 1 precursorHPRD00501
NP_001911.18840NP_003873.1WNT1 inducible signaling pathway protein 1 isoform 1 precursorHPRD16019
NP_001911.11956NP_005219.1epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)HPRD00579
NP_001911.11956NP_005219.1epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)HPRD00501
NP_001911.17373NP_066933.1collagen, type XIV, alpha 1HPRD00379
NP_001911.17373NP_066933.1collagen, type XIV, alpha 1HPRD00501
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1634IPR001611LRRLeucine-rich repeat
1634IPR000372LRR_cys_NLeucine-rich repeat, cysteine-rich flanking region, N-terminal
1634IPR003591LRR_typLeucine-rich repeat, typical subtype
1634PGS2_HUMANP07585IPR001611LRRLeucine-rich repeat
1634PGS2_HUMANP07585IPR000372LRR_cys_NLeucine-rich repeat, cysteine-rich flanking region, N-terminal
1634PGS2_HUMANP07585IPR003591LRR_typLeucine-rich repeat, typical subtype

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