Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1655
Official Symbol:DDX5
Other Aliases:DKFZp686J01190|G17P1|HLR1|HUMP68|p68
See related:HGNC:2746|MIM:180630|HPRD:01615
Chromosome:17
Location:17q21
Gene Description:DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0190
ORGANISM:human
Entrez Gene ID:1655
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:13207
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13207CBCerebellum100.0100.0
13207CTXCerebral cortex100.0100.0
13207HIPHippocampal region100.0100.0
13207HPFHippocampal formation100.0100.0
13207HYHypothalamus98.216030120849692.5791816711426
13207LSXLateral septal complex100.0100.0
13207MBMidbrain89.505943298339885.1407089233398
13207MYMedulla89.945186614990290.1228485107422
13207OLFOlfactory bulb100.0100.0
13207PPons89.545951843261790.0883445739746
13207PALPallidum93.733901977539192.6340408325195
13207RHPRetrohippocampal region100.0100.0
13207sAMYStriatum-like amygdalar nuclei100.0100.0
13207STRStriatum100.0100.0
13207STRdStriatum dorsal region100.0100.0
13207STRvStriatum ventral region100.0100.0
13207THThalamus96.91272735595796.7548828125
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1655GO:0000166IEAFunctionnucleotide binding
1655GO:0003723IEAFunctionRNA binding
1655GO:0003724NASFunctionRNA helicase activity
1655GO:0005524IEAFunctionATP binding
1655GO:0005634NASComponentnucleus
1655GO:0008026IEAFunctionATP-dependent helicase activity
1655GO:0016049NASProcesscell growth
1655GO:0016787IEAFunctionhydrolase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
-10270NP_005849.1A-kinase anchor protein 8HPRD05258
NP_004387.1--CalmodulinHPRD01615
NP_004387.1-AAL00900.1polyproteinBIND180375
NP_004387.110270-AKAP95HPRD01615
NP_004387.110521AAH00595.1DDX17 proteinBIND151427
NP_004387.12099NP_000116.1estrogen receptor 1BIND258481
NP_004387.17157NP_000537.2tumor protein p53BIND210000
NP_004387.12091NP_001427.2fibrillarinHPRD01615
NP_004387.12091NP_001427.2fibrillarinHPRD00617
NP_004387.16885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD04011
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1655DDX5_HUMANP17844IPR001410DEADDEAD/DEAH box helicase
1655DDX5_HUMANP17844IPR011545DEAD/DEAH_NDEAD/DEAH box helicase, N-terminal
1655DDX5_HUMANP17844IPR013701DEAD/DEAH_assocDEAD/H associated
1655DDX5_HUMANP17844IPR000629DEAD_boxATP-dependent helicase, DEAD-box
1655DDX5_HUMANP17844IPR001650Helicase_CHelicase, C-terminal
1655DDX5_HUMANP17844IPR013676NPHI_CNucleoside triphosphatase I, C-terminal
1655DDX5_HUMANP17844IPR012587P68HRP68HR
1655DDX5_HUMANP17844IPR013663SNF2_assoc_bacSNF2 helicase associated, bacterial

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