Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1745
Official Symbol:DLX1
Other Aliases:-
See related:HGNC:2914|MIM:600029
Chromosome:2
Location:2q32
Gene Description:distal-less homeobox 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0245
ORGANISM:human
Entrez Gene ID:1745
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:13390
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13390CBCerebellum20.193899552027417.9386281172435
13390CTXCerebral cortex31.240267594655422.6914375027021
13390HIPHippocampal region25.775045116742520.9333609342575
13390HPFHippocampal formation28.549325803915722.2486634850502
13390HYHypothalamus34.987293750047727.8057968517145
13390LSXLateral septal complex67.833634694417363.0205340385437
13390MBMidbrain14.953843474388110.7678994735082
13390MYMedulla32.278076109786829.3695145299037
13390OLFOlfactory bulb56.480603218078654.6810261408488
13390PPons23.658859250446220.5058140456676
13390PALPallidum20.558782503008817.182112544775
13390RHPRetrohippocampal region34.669669379790625.5557445337375
13390sAMYStriatum-like amygdalar nuclei36.029985636472726.2959572374821
13390STRStriatum19.653669039408415.9861385822296
13390STRdStriatum dorsal region10.00506180524838.10326884190241
13390STRvStriatum ventral region26.418293337027217.808535973231
13390THThalamus15.568091914057712.0593475202719
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1745GO:0003700IEAFunctiontranscription factor activity
1745GO:0005634IEAComponentnucleus
1745GO:0005634NASComponentnucleus
1745GO:0006355IEAProcessregulation of transcription, DNA-dependent
1745GO:0007275NASProcessdevelopment
1745GO:0043565IEAFunctionsequence-specific DNA binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
P561774089-SMAD4HPRD08961
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1745
1745DLX1_HUMANP56177IPR001356HomeoboxHomeobox
1745DLX1_HUMANP56177IPR000047HTH_lambrepressrHelix-turn-helix motif, lambda-like repressor

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