Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:17748
Official Symbol:Mt1
Other Aliases:MT-I|Mt-1
See related:MGI:97171
Chromosome:8
Location:8 C5|8 45.0 cM
Gene Description:metallothionein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC1516
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:Mapping from human
Evidence ID Type:Entrez Gene
Evidence ID:4501
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIC2107
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24567
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:EVIM0764
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15745951
Addiction Drug:ALCOHOL
Addiction Drug Detail:ACUTE ETHANOL ADMINISTRATION
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:2.39
KARG Evidence 4
KARG ID:EVIM0765
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15745951
Addiction Drug:ALCOHOL
Addiction Drug Detail:ACUTE ETHANOL ADMINISTRATION
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Upregulated
Fold Change:2.02
KARG Evidence 5
KARG ID:EVIM0766
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15745951
Addiction Drug:ALCOHOL
Addiction Drug Detail:ACUTE ETHANOL ADMINISTRATION
Addiction Brain Area:Prefrontal Cortex
Drug Effects:Upregulated
Fold Change:4.01
KARG Evidence 6
KARG ID:EVIM1030
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15002731
Addiction Drug:ALCOHOL
Addiction Drug Detail:ACUTE ETHANOL ADMINISTRATION
Addiction Brain Area:Whole Brain
Drug Effects:Upregulated
Fold Change:1.5 :: 1.5
KARG Evidence 7
KARG ID:EVIM1089
ORGANISM:mouse
Entrez Gene ID:17748
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15002731
Addiction Drug:ALCOHOL
Addiction Drug Detail:ACUTE ETHANOL ADMINISTRATION
Addiction Brain Area:Whole Brain
Drug Effects:Upregulated
Fold Change:1.7 :: 1.7
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
17748GO:0005507IDAFunctioncopper ion binding
17748GO:0005764IDAComponentlysosome
17748GO:0005829IDAComponentcytosol
17748GO:0006875IDAProcessmetal ion homeostasis
17748GO:0006882IMPProcesszinc ion homeostasis
17748GO:0007263IMPProcessnitric oxide mediated signal transduction
17748GO:0008270TASFunctionzinc ion binding
17748GO:0046872IDAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
17748MT1_MOUSEP02802IPR000006Metallthion_1Vertebrate metallothionein
17748MT1_MOUSEP02802IPR001008Metallthion_2Mollusc metallothionein, family 2
17748MT1_MOUSEP02802IPR003019Metallthion_Metallothionein superfamily

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