Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1847
Official Symbol:DUSP5
Other Aliases:DUSP|HVH3
See related:HGNC:3071|MIM:603069|HPRD:04349
Chromosome:10
Location:10q25
Gene Description:dual specificity phosphatase 5
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0438
ORGANISM:human
Entrez Gene ID:1847
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:171109
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
240672CBCerebellum100.0100.0
240672CTXCerebral cortex40.554676055908232.2350797653198
240672HIPHippocampal region37.369007110595767.5206909179688
240672HPFHippocampal formation38.913867950439554.9391269683838
240672HYHypothalamus1.043308496475220.833929926156998
240672LSXLateral septal complex16.3337192535413.6568899154663
240672MBMidbrain2.755453824996952.87260925769806
240672MYMedulla13.706770420074518.0722150802612
240672OLFOlfactory bulb36.388497352600142.9273452758789
240672PPons5.802801609039316.18706285953522
240672PALPallidum2.607808351516722.3753879070282
240672RHPRetrohippocampal region42.020177841186542.4497489929199
240672sAMYStriatum-like amygdalar nuclei4.802418589591983.67570182681084
240672STRStriatum10.84565448760998.13210916519165
240672STRdStriatum dorsal region10.18038392066967.66584610939026
240672STRvStriatum ventral region13.68879413604749.22022342681885
240672THThalamus11.72297811508189.81909024715424
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1847GO:0004725TASFunctionprotein tyrosine phosphatase activity
1847GO:0005634IEAComponentnucleus
1847GO:0006470IEAProcessprotein amino acid dephosphorylation
1847GO:0006470TASProcessprotein amino acid dephosphorylation
1847GO:0016787IEAFunctionhydrolase activity
1847GO:0017017IEAFunctionMAP kinase phosphatase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_004410.25595NP_002737.1mitogen-activated protein kinase 3HPRD04349
NP_004410.25595NP_002737.1mitogen-activated protein kinase 3HPRD03479
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1847DUS5_HUMANQ16690IPR000340DS_phosphataseDual specificity protein phosphatase
1847DUS5_HUMANQ16690IPR008343MAPK_phosphMAP kinase phosphatase
1847DUS5_HUMANQ16690IPR001763Rhodanese-likeRhodanese-like
1847DUS5_HUMANQ16690IPR000387TYR_phosphataseTyrosine specific protein phosphatase and dual specificity protein phosphatase

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