Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1937
Official Symbol:EEF1G
Other Aliases:EF1G|GIG35
See related:HGNC:3213|MIM:130593|HPRD:11745
Chromosome:11
Location:11q12.3
Gene Description:eukaryotic translation elongation factor 1 gamma
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0057
ORGANISM:human
Entrez Gene ID:1937
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Downregulated
Fold Change:0.24 :: -0.40 :: -0.42 :: -0.18 :: -0.20 :: -0.08 :: -0.46 :: -0.27 :: -0.21 :: -0.69
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1937GO:0003746NASFunctiontranslation elongation factor activity
1937GO:0005515IPIFunctionprotein binding
1937GO:0005622NASComponentintracellular
1937GO:0005853IEAComponenteukaryotic translation elongation factor 1 complex
1937GO:0006412IEAProcessprotein biosynthesis
1937GO:0006414NASProcesstranslational elongation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001395.11937NP_001395.1eukaryotic translation elongation factor 1 gammaHPRD11745
NP_001395.13035NP_002100.2histidyl-tRNA synthetaseHPRD11745
NP_001395.13035NP_002100.2histidyl-tRNA synthetaseBIND216896
NP_001395.16596NP_003062.2SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3HPRD11745
NP_001395.12058NP_004437.2glutamyl-prolyl tRNA synthetaseBIND216893
NP_001395.110912NP_006696.1growth arrest and DNA-damage-inducible, gammaHPRD11745
NP_001395.17532NP_036611.2tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptideHPRD11745
NP_001395.151520NP_064502.8leucyl-tRNA synthetaseHPRD11745
NP_001395.151520NP_064502.8leucyl-tRNA synthetaseBIND216895
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1937EF1G_HUMANP26641IPR001662EF1_GElongation factor 1, gamma chain
1937EF1G_HUMANP26641IPR004046GST_CGlutathione S-transferase, C-terminal
1937EF1G_HUMANP26641IPR004045GST_NGlutathione S-transferase, N-terminal

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