Knowledgebase for Addiction-Related Genes
Home | Score | Chromosome | Pathway | Advanced Search | BLAST Search | Downloads | Publications | FAQ & Help |   

KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1959
Official Symbol:EGR2
Other Aliases:CMT1D|CMT4E|DKFZp686J1957|FLJ14547|KROX20
See related:HGNC:3239|MIM:129010|HPRD:00551
Chromosome:10
Location:10q21.1
Gene Description:early growth response 2 (Krox-20 homolog, Drosophila)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0597
ORGANISM:human
Entrez Gene ID:1959
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:114090
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13654CBCerebellum21.486781120300323.6139125823975
13654CTXCerebral cortex75.98303985595762.0102596282959
13654HIPHippocampal region41.663751602172955.8049049377441
13654HPFHippocampal formation49.598451614379951.755880355835
13654HYHypothalamus7.300111293792725.20291936397552
13654LSXLateral septal complex26.18306922912620.8331627845764
13654MBMidbrain11.10733938217168.94464731216431
13654MYMedulla16.794505119323715.8158059120178
13654OLFOlfactory bulb72.645469665527364.8374900817871
13654PPons11.01732015609749.29930353164673
13654PALPallidum9.604126930236827.49348020553589
13654RHPRetrohippocampal region62.752859115600649.6545524597168
13654sAMYStriatum-like amygdalar nuclei18.092372894287112.3186359405518
13654STRStriatum41.69636154174832.9130926132202
13654STRdStriatum dorsal region46.023115158081137.252007484436
13654STRvStriatum ventral region44.970827102661132.9157466888428
13654THThalamus18.890143394470213.9577765464783
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1959GO:0003700IDAFunctiontranscription factor activity
1959GO:0005515IPIFunctionprotein binding
1959GO:0005634IEAComponentnucleus
1959GO:0006350IEAProcesstranscription
1959GO:0006355IEAProcessregulation of transcription, DNA-dependent
1959GO:0007420TASProcessbrain development
1959GO:0007422TASProcessperipheral nervous system development
1959GO:0007638IEAProcessmechanosensory behavior
1959GO:0008270IEAFunctionzinc ion binding
1959GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_000390.23054NP_005325.1host cell factor C1 (VP16-accessory protein)HPRD00551
NP_000390.2155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1959EGR2_HUMANP11161IPR000694PRO_richProline-rich region
1959EGR2_HUMANP11161IPR007087Znf_C2H2Zinc finger, C2H2-type
1959EGR2_HUMANP11161IPR007086Znf_C2H2_subZinc finger, C2H2-subtype

© Center for Bioinformatics(CBI), Peking University
Any Comments and suggestions to : KARG GROUP.