Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1961
Official Symbol:EGR4
Other Aliases:NGFI-C|NGFIC|PAT133
See related:HGNC:3241|MIM:128992|HPRD:00550
Chromosome:2
Location:2p13
Gene Description:early growth response 4
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0578
ORGANISM:human
Entrez Gene ID:1961
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:25129
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13656CBCerebellum24.593481540679935.0005283355713
13656CTXCerebral cortex41.245283126831138.1855373382568
13656HIPHippocampal region15.2004604339619.6452436447144
13656HPFHippocampal formation18.968981742858922.0156807899475
13656HYHypothalamus6.214728116989145.0467689037323
13656LSXLateral septal complex33.713269233703629.7121667861938
13656MBMidbrain11.355138778686511.9872975349426
13656MYMedulla15.323620319366516.0188660621643
13656OLFOlfactory bulb32.613952636718830.9991483688354
13656PPons7.542207717895517.64586639404297
13656PALPallidum7.419582724571236.30249464511871
13656RHPRetrohippocampal region24.799169540405324.6703362464905
13656sAMYStriatum-like amygdalar nuclei13.876572132110610.5872025489807
13656STRStriatum30.085469245910624.743260383606
13656STRdStriatum dorsal region31.128282070159925.3934860229492
13656STRvStriatum ventral region35.168351173400928.7281160354614
13656THThalamus19.519316673278818.2486834526062
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1961GO:0003700NASFunctiontranscription factor activity
1961GO:0005634IEAComponentnucleus
1961GO:0006350IEAProcesstranscription
1961GO:0006355IEAProcessregulation of transcription, DNA-dependent
1961GO:0008270IEAFunctionzinc ion binding
1961GO:0008284TASProcesspositive regulation of cell proliferation
1961GO:0046872IEAFunctionmetal ion binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001956.14773NP_775114.1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 isoform CHPRD02730
NP_001956.14773NP_775114.1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 isoform CHPRD00550
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1961EGR4_HUMANQ05215IPR000694PRO_richProline-rich region
1961EGR4_HUMANQ05215IPR007087Znf_C2H2Zinc finger, C2H2-type
1961EGR4_HUMANQ05215IPR007086Znf_C2H2_subZinc finger, C2H2-subtype

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