Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:196883
Official Symbol:ADCY4
Other Aliases:-
See related:HGNC:235|MIM:600292|HPRD:11614
Chromosome:14
Location:14q12
Gene Description:adenylate cyclase 4
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0469
ORGANISM:human
Entrez Gene ID:196883
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:54223
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
104110CBCerebellum12.21938896179217.146559715271
104110CTXCerebral cortex3.861578345298773.05059373378754
104110HIPHippocampal region5.123978137969974.96975708007812
104110HPFHippocampal formation5.561264038085945.05188727378845
104110HYHypothalamus1.737083852291111.81373864412308
104110LSXLateral septal complex0.2679300419986250.197332918643951
104110MBMidbrain2.49968969821933.16400718688965
104110MYMedulla8.649405717849739.13198637962341
104110OLFOlfactory bulb14.923437595367412.9491143226624
104110PPons4.625583231449135.0115852355957
104110PALPallidum4.084816932678224.17523241043091
104110RHPRetrohippocampal region6.304684400558475.14821743965149
104110sAMYStriatum-like amygdalar nuclei5.907664299011235.8538761138916
104110STRStriatum4.741831898689274.05654215812683
104110STRdStriatum dorsal region3.585199505090713.047293394804
104110STRvStriatum ventral region9.436383783817297.29304957389832
104110THThalamus2.086552977561951.99002420902252
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
196883GO:0000287IEAFunctionmagnesium ion binding
196883GO:0004016IEAFunctionadenylate cyclase activity
196883GO:0006171IEAProcesscAMP biosynthesis
196883GO:0007242IEAProcessintracellular signaling cascade
196883GO:0016020IEAComponentmembrane
196883GO:0016021IEAComponentintegral to membrane
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
196883ADCY4_HUMANQ8NFM4IPR001054A/G_cyclaseAdenylyl cyclase class-3/4/guanylyl cyclase
196883ADCY4_HUMANQ8NFM4IPR009398Aden_cycl_likeAdenylate cyclase-like

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