Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:1984
Official Symbol:EIF5A
Other Aliases:EIF-5A|EIF5A1|MGC104255|MGC99547|uORF|uORF A
See related:HGNC:3300|MIM:600187|HPRD:02555
Chromosome:17
Location:17p13-p12
Gene Description:eukaryotic translation initiation factor 5A
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0060
ORGANISM:human
Entrez Gene ID:1984
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15009677
Addiction Drug:COCAINE
Addiction Drug Detail:COCAINE ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:-0.35 :: -1.26 :: 0.84 :: -0.23 :: -1.02 :: -0.91 :: -0.78 :: -0.02 :: -0.78 :: -2.01
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
1984GO:0003676IEAFunctionnucleic acid binding
1984GO:0003743IEAFunctiontranslation initiation factor activity
1984GO:0005515IPIFunctionprotein binding
1984GO:0006412IEAProcessprotein biosynthesis
1984GO:0006413IEAProcesstranslational initiation
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001961.1--Exportin 4HPRD02555
NP_001961.1--XRN2HPRD02555
NP_001961.16125NP_000960.2ribosomal protein L5HPRD02555
NP_001961.16125NP_000960.2ribosomal protein L5HPRD04699
NP_001961.17514NP_003391.1exportin 1HPRD03975
NP_001961.17514NP_003391.1exportin 1HPRD02555
NP_001961.122803NP_036387.25'-3' exoribonuclease 2HPRD10309
NP_001961.1155908NP_057854.1Rev--
NP_001961.1155908NP_057854.1Rev--
NP_001961.1155908NP_057854.1Rev--
NP_001961.1155908NP_057854.1Rev--
NP_001961.1155908NP_057854.1Rev--
NP_001961.1155908NP_057854.1Rev--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
1984IF5A_HUMANP63241IPR001884EIF5A_hypusineEukaryotic initiation factor 5A hypusine (eIF-5A)

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