Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2012
Official Symbol:EMP1
Other Aliases:CL-20|EMP-1|TMP
See related:HGNC:3333|MIM:602333|HPRD:11892
Chromosome:12
Location:12p12.3
Gene Description:epithelial membrane protein 1
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIM0326
ORGANISM:human
Entrez Gene ID:2012
Evidence Type:Microarray
Evidence ID Type:PUBMED
Evidence ID:15816859
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Nucleus Accumbens
Drug Effects:Upregulated
Fold Change:0.77
KARG Evidence 2
KARG ID:QTL0112
ORGANISM:human
Entrez Gene ID:2012
Evidence Type:QTL assay
Evidence ID Type:PUBMED
Evidence ID:NA
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
13731CBCerebellum27.368576049804738.6132202148438
13731CTXCerebral cortex79.260437011718865.1265258789062
13731HIPHippocampal region48.611545562744183.4676208496094
13731HPFHippocampal formation53.620681762695371.3725280761719
13731HYHypothalamus27.669679641723624.0930137634277
13731LSXLateral septal complex27.15622901916520.667818069458
13731MBMidbrain38.157688140869136.5784759521484
13731MYMedulla41.71692657470746.1923789978027
13731OLFOlfactory bulb68.360992431640662.3330307006836
13731PPons34.850624084472741.0053024291992
13731PALPallidum33.078308105468833.4683456420898
13731RHPRetrohippocampal region63.518997192382857.4079322814941
13731sAMYStriatum-like amygdalar nuclei43.44116210937534.921272277832
13731STRStriatum34.338401794433626.9572849273682
13731STRdStriatum dorsal region32.537693023681625.3971061706543
13731STRvStriatum ventral region38.63469314575229.9865112304688
13731THThalamus24.846210479736321.5359058380127
KARG Evidence 3
KARG ID:QTL0112
Trait:METH responses for body temperature
Peak:65
Peak Marker:Nmdar2b
Parents:C57BL/6J x DBA/2J intercross
Evidence ID:8987796
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2012GO:0005624TASComponentmembrane fraction
2012GO:0007275TASProcessdevelopment
2012GO:0008219NRProcesscell death
2012GO:0008283TASProcesscell proliferation
2012GO:0008544TASProcessepidermis development
2012GO:0016020IEAComponentmembrane
2012GO:0016021TASComponentintegral to membrane
2012GO:0016049IEAProcesscell growth
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2012EMP1_HUMANP54849IPR006187ClaudinClaudin tight junction protein
2012EMP1_HUMANP54849IPR003932EMP_1Epithelial membrane protein EMP-1
2012EMP1_HUMANP54849IPR004031PMP22_ClaudinPMP-22/EMP/MP20 and claudin
2012EMP1_HUMANP54849IPR004032PMP22_EMP_MP20PMP-22/EMP/MP20

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