Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2023
Official Symbol:ENO1
Other Aliases:ENO1L1|MBP-1|MPB1|NNE|PPH
See related:HGNC:3350|MIM:172430|HPRD:01400
Chromosome:1
Location:1p36.3-p36.2
Gene Description:enolase 1, (alpha)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0238
ORGANISM:human
Entrez Gene ID:2023
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:13806
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 2
KARG ID:EVIC0452
ORGANISM:human
Entrez Gene ID:2023
Evidence Type:Mapping from rat
Evidence ID Type:Entrez Gene
Evidence ID:24333
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
KARG Evidence 3
KARG ID:EVIP0212
ORGANISM:human
Entrez Gene ID:2023
Evidence Type:Proteomics
Evidence ID Type:PUBMED
Evidence ID:15542695
Addiction Drug:ALCOHOL
Addiction Drug Detail:ALCOHOL ABUSE
Addiction Brain Area:Whole Brain
Drug Effects:Downregulated
Fold Change:0.31
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2023GO:0000015IEAComponentphosphopyruvate hydratase complex
2023GO:0000287IEAFunctionmagnesium ion binding
2023GO:0003677IEAFunctionDNA binding
2023GO:0004634TASFunctionphosphopyruvate hydratase activity
2023GO:0005634IEAComponentnucleus
2023GO:0006096IEAProcessglycolysis
2023GO:0006350IEAProcesstranscription
2023GO:0006355IEAProcessregulation of transcription, DNA-dependent
2023GO:0008243IEAFunctionplasminogen activator activity
2023GO:0016829IEAFunctionlyase activity
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
NP_001419.16885NP_663304.1mitogen-activated protein kinase kinase kinase 7 isoform BHPRD04011
NP_001419.1155871NP_057853.1Tat--
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2023ENOA_HUMANP06733IPR000941EnolaseEnolase

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