Knowledgebase for Addiction-Related Genes
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KARG (Knowledgebase for Addiction Related Genes) >> Gene Entry 
For each addiction related gene, evidences from various strategies have been listed in detail. In addition, each gene were further annotated with various online databases including basic information, gene ontology annotation, protein interaction and domain information.

Basic Information
Gene ID:2119
Official Symbol:ETV5
Other Aliases:ERM
See related:HGNC:3494|MIM:601600|HPRD:09035
Chromosome:3
Location:3q28
Gene Description:ets variant gene 5 (ets-related molecule)
Gene type:protein-coding
Gene Structure:
Genomic Context:
KARG Evidence 1
KARG ID:EVIC0050
ORGANISM:human
Entrez Gene ID:2119
Evidence Type:Mapping from mouse
Evidence ID Type:Entrez Gene
Evidence ID:104156
Addiction Drug:
Addiction Drug Detail:
Addiction Brain Area:
Drug Effects:
Fold Change:
Mapped Allen Brain Atlas (Click to check expression images in Allan Brain Atlas)
Mouse Entrez Gene IDBrain RegionBrain Region DetailExpression LevelExpression Density
104156CBCerebellum15.446996688842841.756778717041
104156CTXCerebral cortex50.050.0
104156HIPHippocampal region21.573139190673836.1099166870117
104156HPFHippocampal formation35.16911697387750.0
104156HYHypothalamus8.922650337219246.66051006317139
104156LSXLateral septal complex37.308109283447330.3821048736572
104156MBMidbrain13.386824607849113.6595630645752
104156MYMedulla10.959600448608412.9571046829224
104156OLFOlfactory bulb45.879913330078146.9107856750488
104156PPons10.983256340026913.5209264755249
104156PALPallidum16.542648315429714.9676704406738
104156RHPRetrohippocampal region50.050.0
104156sAMYStriatum-like amygdalar nuclei23.651069641113321.1135292053223
104156STRStriatum44.751415252685538.3169212341309
104156STRdStriatum dorsal region47.546173095703141.5862312316895
104156STRvStriatum ventral region48.199916839599638.0821151733398
104156THThalamus21.157674789428718.5801868438721
KARG Evidence 2
KARG ID:HOT0049
Entrez Gene ID:2119
RefSeq ID:NM_004454
Position Information:-, Enhancer, 40514bp
Linkage Marker:rs2575
Evidence Type:ASSOCIATION GENOME SCANNING
Evidence Name:PUBMED
Evidence ID:11704927
Addiction Drug:POLYSUBSTANCE
Addiction Drug Detail:POLYSUBSTANCE ABUSE
Gene Ontology
Gene IDGO IDEvidenceGO TypeGO Description
2119GO:0003700TASFunctiontranscription factor activity
2119GO:0005634IEAComponentnucleus
2119GO:0006355IEAProcessregulation of transcription, DNA-dependent
2119GO:0043565IEAFunctionsequence-specific DNA binding
Interaction Information
Gene Product IDInteractant Gene IDInteractant Gene Product IDInteractant Gene Product NameSourceSource ID
Domain Information
Gene IDUniprot/Swissprot IDUniprot/Swissprot ACCInterpro IDInterpro Short DescriptionInterpro Long Description
2119ETV5_HUMANP41161IPR000418EtsEts
2119ETV5_HUMANP41161IPR006715ETS_PEA3_NPEA3-type ETS-domain transcription factor, N-terminal
2119ETV5_HUMANP41161IPR002341HSF_ETS_DNA_bdHSF/ETS, DNA-binding
2119ETV5_HUMANP41161IPR000694PRO_richProline-rich region

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